Sugi Predict

Sugi Predict / Compounds / SCHEMBL2575314

SCHEMBL2575314

SCHEMBL2575314

[O]C(=O)OCc1cccc2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ MEN1 O00255 2/20 0.53
▸ KMT2A Q03164 2/20 0.53
▸ PARP10 Q53GL7 1/20 0.53
▸ SLC1A3 P43003 1/20 0.51
▸ SLC1A2 P43004 1/20 0.51
▸ SLC1A1 P43005 1/20 0.51
▸ ATM Q13315 1/20 0.50
▸ FFAR1 O14842 1/20 0.49
▸ AKR1B1 P15121 1/20 0.49
▸ ACP3 P15309 1/20 0.49
▸ CYP1A2 P05177 2/20 0.47
▸ MTNR1A P48039 1/20 0.46
▸ CTNNB1 P35222 1/20 0.46
▸ PPARG P37231 1/20 0.46
▸ CYP2C9 P11712 1/20 0.46
▸ CYP2C19 P33261 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ NPC1 O15118 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20920798 0.90 EPHX1 (0.47) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL28702056 0.87 TDP1 (0.56) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL21372579 0.87 TDP1 (0.56) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL2575317 0.85 TDP1 (0.59) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL1998527 0.84 MEN1 (0.59) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL1998524 0.84 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL5933367 0.84 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL5077569 0.84 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL5933380 0.84 EPHX1 (0.54) EPHX1TDP1MEN1KMT2APARP10
SCHEMBL487420 0.84 KMT2A (0.55) EPHX1TDP1MEN1KMT2APARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109661601-B Polarizing plate and method for manufacturing same 住友化学株式会社 2022-02-01 — — CN disclosed
CN-109311915-B Sulfonium salt, thermal or photoacid generator, thermal or photocurable composition, and cured product thereof 三亚普罗股份有限公司 2021-09-14 — — CN disclosed
WO-2019078171-A1 METHOD FOR CONCENTRATING OR SEPARATING POLYMER COMPOUND 国立大学法人京都大学 2019-04-25 — — WO disclosed
CN-109311915-A Sulfonium salt, heat or photoacid generator, heat or Photocurable composition and its solidified body 三亚普罗股份有限公司 2019-02-05 — — CN disclosed
EP-2497475-A1 Treatment of laminitis with platelet aggregation inhibitors Dussler, Sabine (DE) 2012-09-12 — — EP disclosed
US-8048897-B2 Cyclohexane derivative, prodrug thereof and salt thereof, and therapeutic agent containing the same for diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2011-11-01 — — US disclosed
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-12-25 — — US disclosed
EP-1783110-A1 NOVEL CYCLOHEXANE DERIVATIVE, PRODRUG THEREOF AND SALT THEREOF, AND THERAPEUTIC AGENT CONTAINING THE SAME FOR DIABETES CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2007-05-09 — — EP disclosed
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 — — US disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 — — EP disclosed
EP-0542411-B1 TETRAHYDROTHIENOPYRIDINE DERIVATIVES, FURO AND PYRROLO ANALOGS THEREOF AND THEIR PREPARATION AND USES FOR INHIBITING BLOOD PLATELET AGGREGATION SANKYO CO (JP) 1998-08-12 — — EP disclosed
US-5691319-A ANTICARCINOGENIC AGENTS SANKYO COMPANY, LIMITED (JP) 1997-11-25 — — US disclosed
EP-0536936-B1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use SANKYO CO (JP) 1996-08-14 — — EP disclosed
US-5389626-A 3-aryloxmethyl-cephalosporin derivatives, and their medical use SANKYO COMPANY, LIMITED (JP) 1995-02-14 — — US disclosed
US-5288726-A Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation UBE INDUSTRIES LIMITED (JP) 1994-02-22 — — US disclosed
EP-0542411-A2 Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation Sankyo Company Limited (JP) 1993-05-19 — — EP disclosed
EP-0536936-A1 Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use Sankyo Company Limited (JP) 1993-04-14 — — EP disclosed
EP-0363223-A2 3-Aryloxymethyl-cephalosporin derivatives, their preparation and their medical use Sankyo Company Limited (JP) 1990-04-11 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR EPHX1 2778/4885TDP1 316/4885MEN1 1357/4885
US-20080318874-A1 Novel Cyclohexane Derivative, Prodrug Thereof and Salt Thereof, and Therapeutic Agent Containing the Same for Diabetes SLC5A1, GPR119, SLC5A2 EPHX1 2189/4885TDP1 3080/4885MEN1 1634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.