SCHEMBL1998527

SCHEMBL1998527

NC(=O)OCc1cccc2ccccc12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.59
KMT2A Q03164 3/20 0.59
PARP10 Q53GL7 2/20 0.59
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
EPHX1 P07099 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
MTNR1A P48039 1/20 0.53
PARP15 Q460N3 1/20 0.49
ATM Q13315 1/20 0.49
FFAR1 O14842 1/20 0.48
AKR1B1 P15121 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
HTT P42858 2/20 0.47
HPGD P15428 1/20 0.47
ACP3 P15309 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.46
CTNNB1 P35222 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13779410 0.87 HPGD (0.53) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL21372579 0.85 TDP1 (0.56) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL28702056 0.85 TDP1 (0.56) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL529123 0.85 KDM4E (0.51) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL2575314 0.84 EPHX1 (0.55) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL2575317 0.84 TDP1 (0.59) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL23932603 0.83 MEN1 (0.52) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL6421722 0.83 MTNR1A (0.58) MEN1KMT2APARP10SLC1A3SLC1A2
SCHEMBL29501710 0.82 SMN1; SMN2 (0.48) PARP10PARP15ALDH1A1CYP1A2
SCHEMBL5933380 0.82 EPHX1 (0.54) MEN1KMT2APARP10SLC1A3SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN claimed
CN-101641332-B Aminated hydroxyquinoline derivatives for the treatment of cancer BIOPHARMED 2014-03-12 CN claimed
CN-101641332-A Aminated hydroxyquinoline derivatives for the treatment of cancer BIOPHARMED SARL FR 2010-02-03 CN claimed
US-20050026994-A1 Use of 2, 4diamino-3-hydroxycarboxylic acid derivatives as proteasome inhibitors FRANCE DENNIS (US) 2005-02-03 US claimed
EP-1435352-A2 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines Wyeth Holdings Corporation (US) 2004-07-07 EP claimed
EP-0618190-B1 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines WYETH CORP (US) 2004-05-19 EP claimed
EP-1289940-A2 EXCITATORY AMINO ACID RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2003-03-12 EP claimed
WO-2001092213-A2 EXCITATORY AMINO ACID RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2001-12-06 WO claimed
US-5371076-A ANTIBIOTICS AMERICAN CYANAMID COMPANY (US) 1994-12-06 US claimed
EP-0618190-A1 9-[(Substituted glycyl)amido]-6-(substituted)-5-hydroxy-6-deoxytetracyclines AMERICAN CYANAMID COMPANY (US) 1994-10-05 EP claimed
JP-58113109-A None JP disclosed
JP-63088106-A None JP disclosed
CN-122056270-A Pesticide suspension concentrate and fertilizer composition thereof 诺力昂化学品国际有限公司 2026-05-19 CN disclosed
CN-117890350-A Preparation of gold-silver alloy-metal organic frame paper-based Raman sensor and application of gold-silver alloy-metal organic frame paper-based Raman sensor in carbaryl detection 济南大学 2024-04-16 CN disclosed
CN-111808011-B High penetration composition and its application 泰飞尔生物医药(苏州)有限公司 2024-02-27 CN disclosed
EP-0272583-A2 5-Substituted amino-4-hydroxy-pentenoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-06-29 EP disclosed
EP-0264106-A2 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-04-20 EP disclosed
JP-S6388106-A CONTROLLING COMPOSITION AGAINST RESISTANT NEPHOTETTIX CINCTICEPS UHLERA NIPPON NOHYAKU CO LTD 1988-04-19 JP disclosed
JP-S58113109-A COMPOSITE INSECTICIDE NIPPON TOKUSHU NOYAKU SEIZO KK 1983-07-05 JP disclosed
JP-S06388106-A 0001-01-01 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050026994-A1 Use of 2, 4diamino-3-hydroxycarboxylic acid derivatives as proteasome inhibitors PSMB3, PSMB2, PSMB1 MEN1 3718/4885KMT2A 588/4885PARP10 1963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.