Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | CPN1 | P15169 | 2/20 | 0.30 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5936757 | 0.97 | LTA4H (0.35) | SLC1A3SLC1A2SLC1A1LTA4HCTSK | |
| SCHEMBL5936761 | 0.95 | LTA4H (0.37) | SLC1A3SLC1A2SLC1A1LTA4HCTSK | |
| SCHEMBL5936845 | 0.93 | MAPT (0.32) | CPN1CPB2ANPEPCTSK | |
| SCHEMBL13543011 | 0.78 | SLC1A3 (0.36) | SLC1A3SLC1A2SLC1A1LTA4HCPN1 | |
| SCHEMBL1246701 | 0.75 | LTA4H (0.37) | SLC1A3SLC1A2SLC1A1LTA4HCTSK | |
| SCHEMBL13543015 | 0.74 | LTA4H (0.38) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 | |
| SCHEMBL5273660 | 0.73 | CTSK (0.39) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 | |
| SCHEMBL28221463 | 0.73 | CYP2D6 (0.34) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL13423682 | 0.73 | LTA4H (0.40) | SLC1A3SLC1A2SLC1A1LTA4HCPB2 | |
| SCHEMBL5936759 | 0.70 | CHRM1 (0.44) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2006-10-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223888-A1 | Valproic acid analogues and pharmaceutical composition thereof | MALT1, HDAC11, GABRA6 | SLC1A3 470/4885SLC1A2 356/4885SLC1A1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.