⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992281 | 0.78 | — | — | |
| SCHEMBL19774119 | 0.76 | — | — | |
| SCHEMBL10835731 | 0.76 | ALDH1A1 (0.53) | — | |
| SCHEMBL8060462 | 0.76 | LMNA (0.47) | — | |
| SCHEMBL11633160 | 0.74 | EPHX1 (0.31) | — | |
| SCHEMBL15443949 | 0.74 | EPHX1 (0.31) | — | |
| SCHEMBL11743030 | 0.72 | EPHX1 (0.30) | — | |
| SCHEMBL11735136 | 0.72 | MAPT (0.35) | — | |
| SCHEMBL16459758 | 0.71 | LMNA (0.47) | — | |
| SCHEMBL3783213 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4500182-A1 | PROGNOSTIC BIOMARKERS | The University of Liverpool (GB) | 2025-02-05 | — | — | EP | disclosed |
| WO-2023180753-A1 | PROGNOSTIC BIOMARKERS | THE UNIVERSITY OF LIVERPOOL (GB) | 2023-09-28 | — | — | WO | disclosed |
| CN-114269982-A | Fabric coating composition | 惠普发展公司，有限责任合伙企业 | 2022-04-01 | — | — | CN | disclosed |
| EP-3885387-A1 | POLYISOCYANATE-BASED POLYADDITION COMPOUNDS HAVING FIVE-MEMBERED CYCLIC IMINOETHER STRUCTURAL ELEMENTS | Covestro Deutschland AG (DE) | 2021-09-29 | — | — | EP | disclosed |
| EP-3885388-A1 | POLYISOCYANATE BASED POLYADDITION COMPOUNDS WITH FIVE-MEMBERED CYCLIC IMINOETHER STRUCTURAL ELEMENTS FOR THE PRODUCTION OF POLYURETHANE PLASTICS | Covestro Deutschland AG (DE) | 2021-09-29 | — | — | EP | disclosed |
| US-8114873-B2 | 1,4-disubstituted naphthalenes as inhibitors of p38 map kinase | ARQULE, INC. (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100311754-A1 | 1,4-Disubstituted Naphthalenes as Inhibitors of P38 Map Kinase | ARQULE, INC. (US) | 2010-12-09 | — | — | US | disclosed |
| US-7829560-B2 | 1,4-disubstituted naphthalenes as inhibitors of P38 MAP kinase | ARQULE, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20080032967-A1 | 1,4-Disubstituted Naphthalenes as Inhibitors of P38 Map Kinase | ARQULE, INC. | 2008-02-07 | — | — | US | disclosed |
| WO-2006010082-A1 | 1,4-DISUBSTITUTED NAPHTALENES AS INHIBITORS OF P38 MAP KINASE | ARQULE, INC. (US) | 2006-01-26 | — | — | WO | disclosed |
| WO-2003067472-A1 | CHEMICAL INFORMATION PROVIDING SYSTEM ON SEARCH ENGINE FOR DEVELOPMENT OF NEW-MATERIAL | NEXT-TECH CO., LTD (KR) | 2003-08-14 | — | — | WO | disclosed |
| EP-0775104-B1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5695737-A | CONTRAST MEDIA FOR NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |
| CN-1156442-A | Dimeric DTPA derivatives and metal complexes thereof, medicaments containing said complexes, their use in diagnosis and therapy and process for preparing said complexes and medicaments | SCHERING AG (DE) | 1997-08-06 | — | — | CN | disclosed |
| EP-0775104-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-05-28 | — | — | EP | disclosed |
| CN-1136805-A | Haloaryl-substituted metal complexes, pharmaceutical preparations containing these complexes, their use in diagnostics and processes for preparing the complexes and preparations | SCHERING CORP (DE) | 1996-11-27 | — | — | CN | disclosed |
| EP-0731784-A1 | ARYL HALIDE SUBSTITUTED METALLIC COMPLEXES, PHARMACEUTICALS CONTAINING THESE COMPLEXES, THEIR USE FOR DIAGNOSTIC PURPOSES, AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1996005167-A1 | DIMER DTPA DERIVATIVES AND THEIR METAL COMPLEXES, PHARMACEUTICALS CONTAINING THE SAME, THEIR USE IN DIAGNOSIS AND THERAPY AND PROCESS FOR PREPARING SAID COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-02-22 | — | — | WO | disclosed |
| WO-1995015306-A1 | ARYL HALIDE SUBSTITUTED METALLIC COMPLEXES, PHARMACEUTICALS CONTAINING THESE COMPLEXES, THEIR USE FOR DIAGNOSTIC PURPOSES, AND METHODS FOR PREPARING THE COMPLEXES AND PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-06-08 | — | — | WO | disclosed |
| US-4414213-A | CARDIOVASCULAR DISORDERS | MEAD JOHNSON & COMPANY (US) | 1983-11-08 | — | — | US | disclosed |