SCHEMBL8060462

SCHEMBL8060462

CC1=NC(CO)(CO)CO1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
GAA P10253 4/20 0.36
ALOX12 P18054 2/20 0.34
AGTR1 P30556 2/20 0.34
CYP1A2 P05177 1/20 0.34
HSP90AA1 P07900 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
EPHX1 P07099 1/20 0.31
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14593296 0.86 LMNA (0.38) LMNAGAA
SCHEMBL13558751 0.79 PRKCA (0.36) LMNAALDH1A1
SCHEMBL22179402 0.79 CNR2 (0.32)
SCHEMBL14626978 0.78 LMNA (0.33) LMNA
SCHEMBL15159899 0.76 LMNA (0.31) LMNAALDH1A1
SCHEMBL12066831 0.76 LMNA (0.46) LMNAGAAALOX12AGTR1CYP1A2
SCHEMBL594114 0.76
SCHEMBL5035786 0.73 LMNA (0.35) LMNAGAA
SCHEMBL9575036 0.72
SCHEMBL14680853 0.71 PRKCA (0.35) LMNACYP3A4CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3778612-B1 PHOSPHATE DERIVATIVES AND USE THEREOF SHANGHAI SHENGYUE PHARMACEUTICAL TECH CO LTD (CN) 2025-02-12 EP disclosed
CN-110317230-B Phosphate derivatives and use thereof 上海昇悦医药科技有限公司 2023-11-07 CN disclosed
EP-3778612-A1 PHOSPHATE DERIVATIVES AND USE THEREOF Zhu, Qing (CN) 2021-02-17 EP disclosed
EP-3778612-A1 PHOSPHATE DERIVATIVES AND USE THEREOF Zhu, Qing (CN) 2021-02-17 EP disclosed
US-20210030773-A1 PHOSPHATE DERIVATIVES AND USE THEREOF Shanghai Shengyue Pharmaceutical Technology Co., Ltd. (CN) 2021-02-04 US disclosed
CN-110317230-A Phosphoric acid salt derivative and application thereof 朱青 2019-10-11 CN disclosed
WO-2019184866-A1 PHOSPHATE DERIVATIVES AND USE THEREOF 朱青 2019-10-03 WO disclosed
EP-2746370-B1 Engine oil AFTON CHEMICAL CORP (US) 2018-02-14 EP disclosed
CN-104844486-A Amino propanediol derivatives, preparation method, drug compositions and uses thereof INST MATERIA MEDICA CAMS 2015-08-19 CN disclosed
US-8888907-B2 Solid phase change ink compositions comprising oxazolines XEROX CORPORATION (US) 2014-11-18 US disclosed
EP-2502619-A2 Systems and methods for delivery of materials Landec Corporation (US) 2012-09-26 EP disclosed
US-20110009571-A1 SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS ALCON RESEARCH, LLC 2011-01-13 US disclosed
US-20100004124-A1 Systems and methods for delivery of materials for agriculture and aquaculture LANDEC CORPORATION 2010-01-07 US disclosed
US-20090263346-A1 Systems and methods for delivery of drugs LANDEC CORPORATION 2009-10-22 US disclosed
US-20090246155-A1 Compositions and methods for personal care LANDEC CORPORATION 2009-10-01 US disclosed
WO-2009073192-A2 SYSTEMS AND METHODS FOR DELIVERY OF MATERIALS LANDEC CORPORATION (US) 2009-06-11 WO disclosed
US-7169817-B2 Bis-aromatic alkanols IRM LLC (BM) 2007-01-30 US disclosed
EP-0008507-B1 DERIVATIVES OF 2-OXAZOLINES AS ANTIOXIDANTS AND COMPOSITIONS THEREOF UNIROYAL, INC. (US) 1985-02-13 EP disclosed
EP-0008507-A1 Derivatives of 2-oxazolines as antioxidants and compositions thereof UNIROYAL, INC. (US) 1980-03-05 EP disclosed
US-4055592-A ATHEROSCLEROSIS MERCK & CO., INC. (US) 1977-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090263346-A1 Systems and methods for delivery of drugs CYCS, CTRC, PPIC LMNA 1770/4885GAA 535/4885ALOX12 1921/4885
US-20090246155-A1 Compositions and methods for personal care PPIC, CYCS, CTRC LMNA 1158/4885GAA 717/4885ALOX12 1778/4885
US-20100004124-A1 Systems and methods for delivery of materials for agriculture and aquaculture CYCS, PCCA, CRYAA LMNA 2119/4885GAA 597/4885ALOX12 1985/4885
US-20210030773-A1 PHOSPHATE DERIVATIVES AND USE THEREOF CXCL12, MIF, FGF23 LMNA 4000/4885GAA 2390/4885ALOX12 1504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.