Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28323722 | 0.79 | IDO1 (0.42) | IDO1 | |
| SCHEMBL28879850 | 0.72 | HSP90AA1 (0.41) | HSP90AA1TLR9 | |
| SCHEMBL7131922 | 0.72 | KMT2A (0.40) | HSP90AA1TLR9 | |
| SCHEMBL6158512 | 0.72 | HSP90AA1 (0.33) | HSP90AA1TLR9IDO1 | |
| SCHEMBL28808700 | 0.68 | HSP90AA1 (0.44) | HSP90AA1TLR9 | |
| SCHEMBL1539490 | 0.66 | HSP90AA1 (0.42) | HSP90AA1TLR9 | |
| SCHEMBL1047305 | 0.65 | PTGDR2 (0.47) | HSP90AA1TLR9 | |
| SCHEMBL196777 | 0.65 | HSP90AA1 (0.46) | HSP90AA1TLR9 | |
| SCHEMBL1047304 | 0.65 | HSP90AA1 (0.46) | HSP90AA1TLR9 | |
| SCHEMBL14135669 | 0.65 | HSP90AA1 (0.41) | HSP90AA1TLR9IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | SANKYO COMPANY, LIMITED (JP) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128756-A1 | Heteroaryl-substituted pyrrole derivatives, their preparation and their therapeutic uses | IL2, IL1A, IL1B | HSP90AA1 1110/4885TLR9 1654/4885IDO1 755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.