SCHEMBL5942467

SCHEMBL5942467

Cc1cnc(F)c(CO)c1C

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CCR1 P32246 1/20 0.34
CCR5 P51681 1/20 0.34
CCR8 P51685 1/20 0.34
GCGR P47871 1/20 0.32
LMNA P02545 1/20 0.31
AGBL2 Q5U5Z8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5942732 0.82 KDM4E (0.36) KDM4EALDH1A1HPGDHSD17B10LMNA
SCHEMBL27779952 0.75 NOS2 (0.39) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL5942538 0.72 KDM4E (0.35) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL5942334 0.72 KCNJ5 (0.35) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL26290099 0.71 NOS2 (0.42) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL5942440 0.71 AOC3 (0.35) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL1758565 0.67 AGXT (0.40) KDM4EALDH1A1HPGDHSD17B10CCR1
SCHEMBL14853213 0.67 NOS3 (0.34)
SCHEMBL27001797 0.67 PDXK (0.37)
SCHEMBL8490451 0.67 CYP2A6 (0.38) HSD17B10AGBL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US claimed
US-20060089390-A1 3-benzoyl-2,4,5-substituted pyridine derivatives or salts thereof and bactericides containing the same ISHIHARA SANGYO KAISHA, LTD. (JP) 2006-04-27 US disclosed