Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 13/20 | 0.46 |
| ▸ | POLB | P06746 | 10/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943217 | 0.88 | KMT2A (0.49) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5943159 | 0.82 | MAPT (0.54) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5943137 | 0.80 | MAPT (0.52) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL13154836 | 0.80 | MAPT (0.57) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL13154838 | 0.78 | MAPT (0.50) | KMT2AMEN1KDM4EALDH1A1GLA | |
| SCHEMBL5943156 | 0.77 | MAPT (0.53) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL15697551 | 0.76 | BCL2L1 (0.54) | LMNA | |
| SCHEMBL2895870 | 0.76 | MAPT (0.68) | KMT2AMEN1KDM4EALDH1A1GLA | |
| SCHEMBL5943192 | 0.75 | MAPT (0.52) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL5943186 | 0.75 | MAPT (0.51) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060281778-A1 | Compounds for inhibiting KSP Kinesin activity | SCHERING CORPORATION | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281778-A1 | Compounds for inhibiting KSP Kinesin activity | KIFC1, KIF5B, KIF2C | KMT2A 716/4885MEN1 1880/4885KDM4E 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.