⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597143 | 0.77 | ADRA2C (0.38) | — | |
| SCHEMBL631042 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL4397378 | 0.65 | — | — | |
| SCHEMBL16819129 | 0.64 | — | — | |
| SCHEMBL472598 | 0.63 | — | — | |
| SCHEMBL18878239 | 0.61 | — | — | |
| SCHEMBL11859284 | 0.61 | MAPT (0.34) | — | |
| SCHEMBL31006320 | 0.58 | — | — | |
| SCHEMBL11858610 | 0.58 | — | — | |
| SCHEMBL6942825 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115002-B2 | Preparation of substituted morphinan-6-ones and salts and intermediates thereof | MALLINCKRODT LLC (US) | 2012-02-14 | — | — | US | claimed |
| US-20100048906-A1 | Preparation of Substituted Morphinan-6-Ones and Salts and Intermediates Thereof | MALLINCKRODT PHARMACEUTICALS IRELAND LIMITED (IE) | 2010-02-25 | — | — | US | claimed |
| US-20080207906-A1 | Synthetic Route to 14-Hydroxyl Opiates Through 1-Halo-Thebaine or Analogs | MALLINCKRODT ENTERPRISES LLC | 2008-08-28 | — | — | US | claimed |
| CN-115110127-B | Hydrophobic bright silver film for inhibiting microbial dirt adhesion growth and preparation method thereof | 常州大学 | 2024-07-16 | — | — | CN | disclosed |
| CN-115110127-A | Hydrophobic bright silver film for inhibiting attachment and growth of microbial dirt and preparation method thereof | 常州大学 | 2022-09-27 | — | — | CN | disclosed |
| US-9458152-B2 | Bicyclic sulfonamide compounds as sodium channel inhibitors | AMGEN INC. (US) | 2016-10-04 | — | — | US | disclosed |
| EP-3008057-A1 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | Amgen Inc. (US) | 2016-04-20 | — | — | EP | disclosed |
| US-20160046626-A1 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. | 2016-02-18 | — | — | US | disclosed |
| US-9212182-B2 | Bicyclic sulfonamide compounds as sodium channel inhibitors | AMGEN INC. (US) | 2015-12-15 | — | — | US | disclosed |
| WO-2014201206-A1 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. (US) | 2014-12-18 | — | — | WO | disclosed |
| US-20140371201-A1 | BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS | AMGEN INC. | 2014-12-18 | — | — | US | disclosed |
| US-4081440-A | Sulfinyl halides and their preparation from penicillin sulfoxides | ELI LILLY AND COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4017667-A | POLLUTION CONTROL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |
| US-4017668-A | POLLUTION CONTROL | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |
| US-4012565-A | Photodegradable polyolefin composition containing an N-halo hydantoin | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-03-15 | — | — | US | disclosed |
| US-4009325-A | Photodegradable polyolefin composition containing an N-halo urethane | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-02-22 | — | — | US | disclosed |
| US-4009324-A | Photodegradable polyolefin composition containing an N-halo lactam | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-02-22 | — | — | US | disclosed |
| US-3968095-A | Photodegradable plastics containing an N-halo amide | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-07-06 | — | — | US | disclosed |
| US-3932352-A | POLYOLEFINS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1976-01-13 | — | — | US | disclosed |
| US-3932559-A | AIR BAGS, TIRES, HOSE | UNIROYAL INC. (US) | 1976-01-13 | — | — | US | disclosed |