Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | AHCY | P23526 | 3/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5943937 | 0.91 | DOT1L (0.52) | DOT1LADORA3ADORA2AAHCYHSP90B1 | |
| SCHEMBL5944004 | 0.74 | DOT1L (0.61) | DOT1LADORA3ADORA2AAHCYHSP90B1 | |
| SCHEMBL30238902 | 0.71 | DOT1L (0.65) | DOT1LAHCYCARM1RXFP1KMT2A | |
| SCHEMBL6298535 | 0.69 | ADORA2A (0.53) | DOT1LADORA3ADORA2AAHCYHSP90B1 | |
| SCHEMBL30239396 | 0.68 | DOT1L (0.57) | DOT1LAHCYRXFP1KMT2APRKACA | |
| SCHEMBL9970273 | 0.68 | DOT1L (0.69) | DOT1LAHCYCARM1RXFP1PRKACA | |
| SCHEMBL9970168 | 0.68 | DOT1L (0.69) | DOT1LAHCYCARM1RXFP1PRKACA | |
| SCHEMBL9970708 | 0.67 | DOT1L (0.61) | DOT1LAHCYCARM1RXFP1KMT2A | |
| SCHEMBL9970202 | 0.66 | DOT1L (0.61) | DOT1LAHCYCARM1RXFP1PRKACA | |
| SCHEMBL15829716 | 0.66 | DOT1L (0.61) | DOT1LAHCYCARM1RXFP1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211045-A1 | Fluorescently tagged ligands | CELLAURA TECHNOLOGIES LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |