Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.61 |
| ▸ | AHCY | P23526 | 2/20 | 0.53 |
| ▸ | PRKACA | P17612 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944101 | 0.83 | ADORA3 (0.56) | AHCYPRKACATSHRCYP2C19HSP90AA1 | |
| SCHEMBL5943937 | 0.81 | DOT1L (0.52) | DOT1LAHCYPRKACAADORA3HSP90B1 | |
| SCHEMBL5944284 | 0.77 | ADORA3 (0.53) | AHCYTSHRCYP2C19HSP90AA1ADORA3 | |
| SCHEMBL29540124 | 0.74 | DOT1L (0.61) | DOT1LAHCYPRKACA | |
| SCHEMBL9970636 | 0.74 | DOT1L (0.63) | DOT1LAHCYPRKACARXFP1 | |
| SCHEMBL5944111 | 0.74 | DOT1L (0.47) | DOT1LAHCYPRKACATSHRCYP2C19 | |
| SCHEMBL9970168 | 0.72 | DOT1L (0.69) | DOT1LAHCYPRKACARXFP1 | |
| SCHEMBL9970273 | 0.72 | DOT1L (0.69) | DOT1LAHCYPRKACARXFP1 | |
| SCHEMBL9970243 | 0.72 | DOT1L (0.76) | DOT1LAHCYPRKACARXFP1 | |
| SCHEMBL11054727 | 0.72 | DOT1L (0.65) | DOT1LAHCYPRKACAADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211045-A1 | Fluorescently tagged ligands | CELLAURA TECHNOLOGIES LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |