Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | AHCY | P23526 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944111 | 0.91 | DOT1L (0.47) | DOT1LADORA3ADORA2AAHCYPRKACA | |
| SCHEMBL5944004 | 0.81 | DOT1L (0.61) | DOT1LADORA3ADORA2AAHCYPRKACA | |
| SCHEMBL6298535 | 0.71 | ADORA2A (0.53) | DOT1LADORA3ADORA2AAHCYHSP90B1 | |
| SCHEMBL9970636 | 0.70 | DOT1L (0.63) | DOT1LAHCYPRKACA | |
| SCHEMBL11193799 | 0.69 | DOT1L (0.52) | DOT1LAHCYPRKACA | |
| SCHEMBL9970273 | 0.69 | DOT1L (0.69) | DOT1LAHCYPRKACA | |
| SCHEMBL9970168 | 0.69 | DOT1L (0.69) | DOT1LAHCYPRKACA | |
| SCHEMBL9970243 | 0.69 | DOT1L (0.76) | DOT1LAHCYPRKACA | |
| SCHEMBL9970708 | 0.69 | DOT1L (0.61) | DOT1LAHCYPRKACA | |
| SCHEMBL31001519 | 0.68 | DOT1L (0.57) | DOT1LAHCYPRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211045-A1 | Fluorescently tagged ligands | CELLAURA TECHNOLOGIES LIMITED (GB) | 2006-09-21 | — | — | US | disclosed |