SCHEMBL5947

SCHEMBL5947

O=C(O)c1ccc2[nH]cnc2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.53
ALDH1A1 P00352 5/20 0.53
HPGD P15428 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
RAB9A P51151 4/20 0.53
HTT P42858 2/20 0.53
HDAC6 Q9UBN7 1/20 0.50
CTNNB1 P35222 1/20 0.49
WNT3A P56704 1/20 0.49
TDP1 Q9NUW8 4/20 0.44
SIRT2 Q8IXJ6 1/20 0.44
SIRT1 Q96EB6 1/20 0.44
ENPP2 Q13822 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HSP90AA1 P07900 1/20 0.44
ESR2 Q92731 1/20 0.44
NPC1 O15118 4/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9928726 0.98 KDM4E (0.51) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL28066117 0.87 KDM4E (0.43) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL10468390 0.86 HTT (0.50) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL5946 0.85 RAB9A (0.71) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL2356958 0.84 RAB9A (0.42) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
Quinoline SCHEMBL28259514 0.84 ALDH1A1 (0.47) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
Piperonylic Acid SCHEMBL8733052 0.84 ALDH1A1 (0.63) ALDH1A1HPGDSMN1; SMN2RAB9ACTNNB1
Ammonia Solution, Strong SCHEMBL28553547 0.84 RAB9A (0.69) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL3776189 0.84 SLC2A1 (0.59) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A
SCHEMBL476588 0.84 AR (0.52) KDM4EALDH1A1HPGDSMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118580748-B Manufacturing method of corrosion-resistant aluminum alloy material for ship manufacturing 山东雪地铝业科技有限公司 2025-03-18 CN claimed
CN-119504603-A Micromolecular compound DBIC and preparation method and application thereof 厦门大学 2025-02-25 CN claimed
CN-119230764-A High-rate lead-acid battery negative electrode material and preparation method thereof 江苏欧力特能源科技有限公司 2024-12-31 CN claimed
EP-4470050-A1 METHOD FOR MANUFACTURING A PROTECTED NEGATIVE ELECTRODE AND THE RESULTING NEGATIVE ELECTRODE Hydro-Québec (CA) 2024-12-04 EP claimed
CN-119060354-A Magnetic quaternized ZIFs nano particles and modified ultrafiltration membrane thereof 吉林大学 2024-12-03 CN claimed
CN-118834382-A Preparation method of intrinsic antibacterial nylon based on end capping strategy 湘潭大学 2024-10-25 CN claimed
CN-118812520-A Benzimidazole-6-carboxylic acid compound and application thereof 南京羚诺生物医药技术研究院有限公司 2024-10-22 CN claimed
CN-118580748-A Manufacturing method of corrosion-resistant aluminum alloy material for ship manufacturing 山东雪地铝业科技有限公司 2024-09-03 CN claimed
CN-118359669-A Metal organic frame material and preparation method and application thereof 北京放射性核素实验室 2024-07-19 CN claimed
CN-115888413-B ZIFs particle loaded nanotube modified polymer-based ultrafiltration membrane, and preparation method and application thereof 吉林大学 2024-07-12 CN claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-5420313-A Catalyst and process for the epoxidation of olefinic compounds BP CHEMICALS LIMITED (GB) 1995-05-30 US claimed
EP-0623389-A1 Catalyst and process for the epoxidation of olefinic compounds BP Chemicals Limited (GB) 1994-11-09 EP claimed
EP-0283504-A1 COMPOUNDS FISONS plc (GB) 1988-09-28 EP claimed
WO-1988002367-A1 COMPOUNDS FISONS PLC (GB) 1988-04-07 WO claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed