SCHEMBL11673262

SCHEMBL11673262

CC(=Cc1ccc(N(c2ccccc2)c2ccccc2)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.69
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
HTT P42858 1/20 0.45
TBXAS1 P24557 4/20 0.44
TP53 P04637 1/20 0.42
APEX1 P27695 6/20 0.41
TRPM8 Q7Z2W7 1/20 0.41
SLC16A3 O15427 1/20 0.41
SLC16A1 P53985 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16657539 0.89 AKR1C3 (0.53) AKR1C3ALDH1A1LMNAGAAMAPT
SCHEMBL16353249 0.83 AKR1C3 (0.51) AKR1C3ALDH1A1MAPTKMT2ATBXAS1
SCHEMBL37034 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1KMT2AHTTTBXAS1
SCHEMBL16568719 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1KMT2AHTTTBXAS1
SCHEMBL581982 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1KMT2AHTTTBXAS1
SCHEMBL41906 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1KMT2AHTTTBXAS1
SCHEMBL2462983 0.82 AKR1C3 (0.82) AKR1C3ALDH1A1HTTTBXAS1TP53
SCHEMBL2462984 0.82 AKR1C3 (0.82) AKR1C3ALDH1A1HTTTBXAS1TP53
SCHEMBL14923070 0.82 ALDH1A1 (0.49) AKR1C3ALDH1A1LMNAGAAMAPT
SCHEMBL11673166 0.81 TP53 (0.58) AKR1C3ALDH1A1LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4018607-A Crystalline organic pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed
US-4018606-A Organic azo pigment sensitizers for photoconductive layers EASTMAN KODAK COMPANY (US) 1977-04-19 US disclosed