Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500020 | 1.00 | AKR1C3 (0.62) | AKR1C3THRBATMALDH1A1KDM4E | |
| SCHEMBL1237225 | 1.00 | AKR1C3 (0.62) | AKR1C3THRBATMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9445569 | 0.98 | AKR1C3 (0.60) | AKR1C3THRBATMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9445568 | 0.98 | AKR1C3 (0.60) | AKR1C3THRBATMALDH1A1KDM4E | |
| SCHEMBL502730 | 0.89 | THRB (0.51) | AKR1C3THRBATMALDH1A1KDM4E | |
| SCHEMBL502731 | 0.89 | THRB (0.51) | AKR1C3THRBATMALDH1A1KDM4E | |
| SCHEMBL9099221 | 0.89 | KDM4E (0.51) | AKR1C3THRBATMALDH1A1KDM4E | |
| SCHEMBL2443290 | 0.86 | ALDH1A1 (0.55) | THRBATMALDH1A1KDM4EMAPT | |
| SCHEMBL2443292 | 0.86 | ALDH1A1 (0.55) | THRBATMALDH1A1KDM4EMAPT | |
| SCHEMBL2462984 | 0.85 | AKR1C3 (0.82) | AKR1C3ALDH1A1KDM4EAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841380-B1 | Method of making polymeric binders and use thereof in antifouling paints | WITCO GMBH (DE) | 1999-08-25 | — | — | EP | claimed |
| EP-0841380-A1 | Method of making polymeric binders and use thereof in antifouling paints | Witco GmbH (DE) | 1998-05-13 | — | — | EP | claimed |
| US-5374487-A | Compatible polymeric mixtures | ROHM GMBH (DE) | 1994-12-20 | — | — | US | claimed |
| EP-4351553-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt GmbH (DE) | 2024-04-17 | — | — | EP | disclosed |
| EP-3233794-B1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS LLC (US) | 2023-02-01 | — | — | EP | disclosed |
| WO-2022258792-A1 | NOVEL ANTI-FIBROTIC DRUGS | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2022-12-15 | — | — | WO | disclosed |
| US-20220315553-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | ADT PHARMACEUTICALS, LLC (US) | 2022-10-06 | — | — | US | disclosed |
| US-11198679-B2 | Method of treating or preventing Ras-mediated diseases | ADT PHARMACEUTICALS, LLC (US) | 2021-12-14 | — | — | US | disclosed |
| US-11130744-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | ADT PHARMACEUTICALS, LLC (US) | 2021-09-28 | — | — | US | disclosed |
| US-10981886-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | ADT PHARMACEUTICALS, LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10975054-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | ADT PHARMACEUTICALS, LLC (US) | 2021-04-13 | — | — | US | disclosed |
| US-5218050-A | COMPATIBLE POLYMER BLENDS | ROHM GMBH CHEMISCHE FABRIK (DE) | 1993-06-08 | — | — | US | disclosed |
| EP-0372213-B1 | PROTECTIVE METHYCRYLATE LAYER FOR POLYCARBONATE, CONTAINING A UV ABSORBER | RÖHM GMBH (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0368094-B1 | IMPACT-RESISTANT PROTECTION METHACRYLATE LAYER CONTAINING A UV ABSORBER FOR POLYCARBONATE | RÖHM GMBH (DE) | 1992-05-06 | — | — | EP | disclosed |
| EP-0477726-A1 | Ternary mixtures of polymers | RÖHM GMBH (DE) | 1992-04-01 | — | — | EP | disclosed |
| EP-0462505-A2 | Compatible polymer blends | RÖHM GMBH (DE) | 1991-12-27 | — | — | EP | disclosed |
| WO-1991011490-A1 | COMPATIBLE POLYARYLACRYLATE AND POLYESTER MIXTURES | RÖHM GMBH (DE) | 1991-08-08 | — | — | WO | disclosed |
| EP-0440034-A1 | Compatible polymer blends | RÖHM GMBH (DE) | 1991-08-07 | — | — | EP | disclosed |
| EP-0372213-A1 | Protective methycrylate layer for polycarbonate, containing a UV absorber | RÖHM GMBH (DE) | 1990-06-13 | — | — | EP | disclosed |
| EP-0368094-A1 | Impact-resistant protection methacrylate layer containing a UV absorber for polycarbonate | RÖHM GMBH (DE) | 1990-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315553-A1 | INDENYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND MEDICAL USES THEREOF | INSRR, INSR, BRCA1 | AKR1C3 532/4885THRB 1359/4885ATM 1070/4885 |
| US-11198679-B2 | Method of treating or preventing Ras-mediated diseases | KRAS, NRAS, HRAS | AKR1C3 381/4885THRB 822/4885ATM 2097/4885 |
| US-11130744-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | INSRR, INSR, BRCA1 | AKR1C3 532/4885THRB 1359/4885ATM 1070/4885 |
| US-10981886-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | INSRR, INSR, BRCA1 | AKR1C3 532/4885THRB 1359/4885ATM 1070/4885 |
| US-10975054-B2 | Indenyl compounds, pharmaceutical compositions, and medical uses thereof | INSRR, INSR, BRCA1 | AKR1C3 532/4885THRB 1359/4885ATM 1070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.