Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5950993 | 0.91 | ALDH1A1 (0.32) | KDM4EALDH1A1ESR1POLBHTT | |
| Hydrochloric Acid SCHEMBL6056185 | 0.87 | ALDH1A1 (0.31) | ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL3275850 | 0.75 | SLC6A4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL3759506 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL339001 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1HTTKMT2A | |
| Hydrochloric Acid SCHEMBL7728452 | 0.69 | MAPT (0.34) | KDM4EALDH1A1ESR1POLBHTT | |
| Hydrochloric Acid SCHEMBL7734558 | 0.69 | MAPT (0.34) | KDM4EALDH1A1ESR1POLBHTT | |
| Hydrochloric Acid SCHEMBL7061937 | 0.69 | NOTUM (0.34) | KDM4EALDH1A1ESR1POLBHTT | |
| Hydrochloric Acid SCHEMBL5604466 | 0.67 | SLC6A4 (0.33) | ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL7936151 | 0.67 | NPC1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019157-B2 | Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process | CHISSO CORPORATION (JP) | 2006-03-28 | — | — | US | disclosed |
| US-20030149200-A1 | Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process | CHISSO PETROCHEMICAL CORPORATION | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149200-A1 | Metallocene compounds, production process for olefin polymers using catalysts containing them and olefin polymers produced by the production process | ZYX, MLX, ZFX | KDM4E 433/4885ALDH1A1 862/4885ESR1 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.