Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5950809 | 1.00 | BDKRB1 (0.49) | BDKRB1OPRD1 | |
| SCHEMBL5950807 | 0.89 | BDKRB1 (0.40) | BDKRB1OPRD1 | |
| SCHEMBL5950808 | 0.89 | BDKRB1 (0.40) | BDKRB1OPRD1 | |
| SCHEMBL3530897 | 0.84 | KDM4C (0.39) | OPRD1 | |
| SCHEMBL3530895 | 0.84 | KDM4C (0.39) | OPRD1 | |
| SCHEMBL3535779 | 0.77 | ACHE (0.41) | BDKRB1 | |
| SCHEMBL3535777 | 0.77 | ACHE (0.41) | BDKRB1 | |
| SCHEMBL5183278 | 0.75 | BDKRB1 (0.68) | BDKRB1 | |
| SCHEMBL12010869 | 0.75 | BDKRB1 (0.43) | BDKRB1OPRD1 | |
| SCHEMBL13189256 | 0.75 | HRH3 (0.49) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111347-A1 | Substituted sulfones and methods of use | AMGEN INC. (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111347-A1 | Substituted sulfones and methods of use | SULT2A1, STS, SULT1A1 | BDKRB1 419/4885OPRD1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.