Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | S100B | P04271 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499783 | 0.85 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL3926124 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL17659019 | 0.80 | KMT2A (0.42) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL17659703 | 0.78 | MEN1 (0.40) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL9831848 | 0.78 | HTR1A (0.47) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL20424608 | 0.77 | MAPT (0.45) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL11441903 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL27810301 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTMEN1GAA | |
| SCHEMBL20424766 | 0.74 | MAPT (0.43) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 | |
| SCHEMBL21598636 | 0.74 | ALDH1A1 (0.53) | ALDH1A1KMT2AMAPTMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | ALDH1A1 2415/4885KMT2A 891/4885MAPT 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.