Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836670 | 0.87 | MAOA (0.59) | ESR2ESR1MAOAGAAMGAM | |
| SCHEMBL31671127 | 0.81 | AHR (0.49) | ALOX5DYRK1AAHRMAOAGAA | |
| SCHEMBL2412683 | 0.81 | AHR (0.49) | ALOX5DYRK1AAHRMAOAGAA | |
| SCHEMBL3886077 | 0.81 | ALOX5 (0.58) | ESR2ALOX5ESR1DYRK1AAHR | |
| SCHEMBL24086751 | 0.79 | AHR (0.46) | ESR2ALOX5ESR1AHRMAOA | |
| SCHEMBL17987528 | 0.79 | MAPT (0.55) | ALOX5DYRK1AAHRMAOAGAA | |
| SCHEMBL30018586 | 0.79 | AHR (0.54) | ALOX5AHRKDM4EMEN1MAPT | |
| SCHEMBL30286404 | 0.79 | AHR (0.46) | ESR2ALOX5ESR1AHRMAOA | |
| SCHEMBL3873780 | 0.79 | ALOX5 (0.47) | ESR2ALOX5DYRK1AAHRMAOA | |
| SCHEMBL19041865 | 0.79 | AHR (0.46) | ALOX5DYRK1AAHRMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | ESR2 2647/4885ALOX5 4799/4885ESR1 2258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.