Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.60 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3066323 | 0.93 | ACHE (0.64) | ACHEBRD4CREBBPPARP10PARP11 | |
| SCHEMBL5952058 | 0.90 | ACHE (0.60) | ACHEBRD4CREBBPPARP10PARP11 | |
| SCHEMBL5952357 | 0.84 | ACHE (0.57) | ACHEBRD4CREBBPPARP10PARP11 | |
| SCHEMBL5952394 | 0.84 | ACHE (0.57) | ACHEBRD4CREBBPHCRTR1HCRTR2 | |
| SCHEMBL5952316 | 0.81 | ACHE (0.77) | ACHEBRD4PARP10PARP11HTR7 | |
| SCHEMBL5952009 | 0.81 | ACHE (0.62) | ACHEBRD4CSNK2A2CSNK2A1 | |
| SCHEMBL5952816 | 0.80 | ACHE (0.54) | ACHEBRD4CREBBP | |
| SCHEMBL5952877 | 0.80 | ACHE (0.60) | ACHEBRD4CSNK2A2CSNK2A1 | |
| SCHEMBL5952480 | 0.80 | ACHE (0.56) | ACHEBRD4CREBBPPARP10PARP11 | |
| SCHEMBL5951545 | 0.80 | ACHE (0.65) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3022238-B1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-09-20 | — | — | EP | disclosed |
| EP-3022238-B1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2017-09-20 | — | — | EP | disclosed |
| US-9745390-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745390-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-29 | — | — | US | disclosed |
| US-9745390-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-08-29 | — | — | US | disclosed |
| EP-3022238-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| US-20160130374-A1 | Metallocenes and Catalyst Compositions Derived Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-05-12 | — | — | US | disclosed |
| US-20160130374-A1 | Metallocenes and Catalyst Compositions Derived Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-05-12 | — | — | US | disclosed |
| US-20160130374-A1 | Metallocenes and Catalyst Compositions Derived Therefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2016-05-12 | — | — | US | disclosed |
| US-9249239-B2 | Metallocenes and catalyst compositions derived therefrom | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2016-02-02 | — | — | US | disclosed |
| WO-2015009470-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025205-A1 | Metallocenes and Catalyst Compositions Derived Tehrefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-20150025205-A1 | Metallocenes and Catalyst Compositions Derived Tehrefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-20150025205-A1 | Metallocenes and Catalyst Compositions Derived Tehrefrom | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| WO-2015009470-A1 | METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150025205-A1 | Metallocenes and Catalyst Compositions Derived Tehrefrom | TERF2, TERT, TERF2IP | ACHE 2798/4885BRD4 173/4885CREBBP 2918/4885 |
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | ACHE 839/4885BRD4 3097/4885CREBBP 2331/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | ACHE 820/4885BRD4 3045/4885CREBBP 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.