SCHEMBL8729779

SCHEMBL8729779

CCc1cc(Cc2cc(CC)c(N)cc2CC)c(CC)cc1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
ALOX15 P16050 2/20 0.44
CYP1A2 P05177 1/20 0.44
CASP7 P55210 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
AR P10275 1/20 0.39
POLB P06746 2/20 0.37
MAPT P10636 2/20 0.37
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
HTT P42858 2/20 0.34
NOS3 P29474 1/20 0.34
NOS1 P29475 1/20 0.34
NOS2 P35228 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11468902 0.92 AR (0.42) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL832574 0.87 ALDH1A1 (0.43) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL5382583 0.85 AR (0.39) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL118865 0.84 ALDH1A1 (0.46) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL8732134 0.81 ALDH1A1 (0.64) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL25559002 0.81 AR (0.41) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL29639033 0.81 PTK2 (0.44) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL5951845 0.81 PTK2 (0.44) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL10702908 0.80 DHFR (0.38) ALDH1A1ALOX15CYP1A2CASP7HIF1A
SCHEMBL337159 0.79 ALDH1A1 (0.40) ALDH1A1ALOX15CYP1A2CASP7HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5725948-A POLYIMIDE FROM A BISMALEIMIDE AND A DIAMINE TOMOEGAWA PAPER CO., LTD. (JP) 1998-03-10 US disclosed