Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.30 |
| ▸ | METAP1 | P53582 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL637333 | 0.94 | ALDH1A1 (0.35) | P2RX3ALDH1A1KDM4ERXFP1NTRK1 | |
| Triphosphate SCHEMBL7453135 | 0.92 | P2RX3 (0.35) | P2RX3 | |
| Triphosphate SCHEMBL9104232 | 0.90 | P2RX3 (0.36) | P2RX3 | |
| Purine SCHEMBL27554272 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4ERXFP1NTRK1FDPS | |
| Purine SCHEMBL5989434 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4ERXFP1NTRK1FDPS | |
| Purine SCHEMBL595231 | 0.87 | ALDH1A1 (0.39) | ALDH1A1KDM4ERXFP1NTRK1FDPS | |
| Purine SCHEMBL2676962 | 0.84 | ALDH1A1 (0.41) | ALDH1A1KDM4ERXFP1NTRK1FDPS | |
| Purine SCHEMBL28271 | 0.80 | ALDH1A1 (0.39) | ALDH1A1KDM4ERXFP1METAP2METAP1 | |
| Purine SCHEMBL28164598 | 0.80 | ALDH1A1 (0.44) | ALDH1A1KDM4ERXFP1METAP2METAP1 | |
| Purine SCHEMBL3158 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2812441-A1 | NUCLEIC ACID LIGATION METHOD | Wisconsin Alumni Research Foundation (US) | 2014-12-17 | — | — | EP | claimed |
| WO-2013119690-A1 | NUCLEIC ACID LIGATION METHOD | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-08-15 | — | — | WO | claimed |
| US-20130203635-A1 | NUCLEIC ACID LIGATION METHOD | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-08-08 | — | — | US | claimed |
| CN-1735693-A | Method for in vitro screening of 2' -substituted nucleic acids | ARCHEMIX CORP (US) | 2006-02-15 | — | — | CN | claimed |
| US-20230346827-A1 | TREATMENT OF CORONAVIRUS INFECTIONS | TX MEDIC AB (SE) | 2023-11-02 | — | — | US | disclosed |
| EP-4135719-A1 | TREATMENT OF CORONAVIRUS INFECTIONS | TX Medic AB (SE) | 2023-02-22 | — | — | EP | disclosed |
| CN-108472371-B | EGFR antibody-drug conjugate and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| WO-2021211043-A1 | TREATMENT OF CORONAVIRUS INFECTIONS | TX MEDIC AB (SE) | 2021-10-21 | — | — | WO | disclosed |
| US-10894946-B2 | Multiloop engineered heart muscle tissue | TISSUE SYSTEMS HOLDING GMBH (DE) | 2021-01-19 | — | — | US | disclosed |
| US-20200140820-A1 | MULTILOOP ENGINEERED HEART MUSCLE TISSUE | UNIVERSITATSKLINIKUM HAMBURG-EPPENDORF (DE) | 2020-05-07 | — | — | US | disclosed |
| US-10494605-B2 | Multiloop engineered heart muscle tissue | TISSUE SYSTEMS HOLDING GMBH (DE) | 2019-12-03 | — | — | US | disclosed |
| CN-107653330-A | A kind of multiple PCR reagent kit and its discrimination method of quick discriminating On Planthopperss | 中国水稻研究所 | 2018-02-02 | — | — | CN | disclosed |
| WO-1998045313-A1 | NOVEL UNCOUPLING PROTEIN AND METHODS OF USE | AMYLIN PHARMACEUTICALS, INC. (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998042869-A1 | MAMMALIAN DNA PRIMASE SCREENS AND ACTIVITY MODULATING AGENTS | GERON CORPORATION (US) | 1998-10-01 | — | — | WO | disclosed |
| US-5801184-A | Carbon monoxide dependent guanylyl cyclase modifiers and methods of use | SPECTRUM PHARMACEUTICALS, INC. | 1998-09-01 | — | — | US | disclosed |
| CN-1154065-A | Carbon monoxide dependent guanylyl cyclase effectors | GLASKY ALVIN J (US) | 1997-07-09 | — | — | CN | disclosed |
| EP-0772440-A1 | CARBON MONOXIDE DEPENDENT GUANYLYL CYCLASE MODIFIERS | GLASKY, Alvin J. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996006621-A1 | METAL COMPLEX CONTAINING OLIGONUCLEOSIDE CLEAVAGE COMPOUNDS AND THERAPIES | GENTA INCORPORATED (US) | 1996-03-07 | — | — | WO | disclosed |
| WO-1996003125-A1 | CARBON MONOXIDE DEPENDENT GUANYLYL CYCLASE MODIFIERS | GLASKY ALVIN J (US) | 1996-02-08 | — | — | WO | disclosed |
| US-5447939-A | Purine derivatives used for long term modification of neural activity in mammals, for treatment of mammalian neurological diseases, and for inducing long term changes in membrane potential of mammalian neuron | SPECTRUM PHARMACEUTICALS, INC. | 1995-09-05 | — | — | US | disclosed |