Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL637333

O=P(O)(O)OP(=O)(O)O.c1ncc2[nH]cnc2n1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
KDM4E B2RXH2 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
P2RX3 P56373 1/20 0.33
FDPS P14324 2/20 0.32
BLM P54132 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
NTRK1 P04629 1/20 0.30
PDPK1 O15530 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphosphate SCHEMBL595229 0.94 P2RX3 (0.38) ALDH1A1KDM4ERXFP1P2RX3FDPS
Purine SCHEMBL27554272 0.90 ALDH1A1 (0.39) ALDH1A1KDM4ERXFP1FDPSNTRK1
Purine SCHEMBL5989434 0.90 ALDH1A1 (0.39) ALDH1A1KDM4ERXFP1FDPSNTRK1
Purine SCHEMBL595231 0.90 ALDH1A1 (0.39) ALDH1A1KDM4ERXFP1FDPSNTRK1
Purine SCHEMBL2676962 0.87 ALDH1A1 (0.41) ALDH1A1KDM4ERXFP1FDPSNTRK1
Triphosphate SCHEMBL7453135 0.86 P2RX3 (0.35) P2RX3
Triphosphate SCHEMBL9104232 0.84 P2RX3 (0.36) P2RX3
Purine SCHEMBL28271 0.83 ALDH1A1 (0.39) ALDH1A1KDM4ERXFP1PDPK1
Purine SCHEMBL28164598 0.82 ALDH1A1 (0.44) ALDH1A1KDM4ERXFP1PDPK1
Purine SCHEMBL2120554 0.82 ALDH1A1 (0.47) ALDH1A1KDM4ERXFP1PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis GENOMATICA, INC. (US) 2026-01-20 US disclosed
US-20240294950-A1 MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS AGAIN BIO APS (DK) 2024-09-05 US disclosed
EP-4421181-A2 NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY Genomatica, Inc. (US) 2024-08-28 EP disclosed
EP-4389904-A2 MICROORGANISMS FOR PRODUCING 4C-5C COMPOUNDS WITH UNSATURATION AND METHODS RELATED THERETO Genomatica, Inc. (US) 2024-06-26 EP disclosed
US-11932893-B2 Microorganisms and methods for producing alkenes GENOMATICA, INC. (US) 2024-03-19 US disclosed
EP-3741865-B1 NON-NATURAL MICROBIAL ORGANISMS WITH IMPROVED ENERGETIC EFFICIENCY GENOMATICA INC (US) 2024-03-13 EP disclosed
EP-3164495-B1 MICROORGANISMS FOR PRODUCING 4C-5C COMPOUNDS WITH UNSATURATION AND METHODS RELATED THERETO GENOMATICA INC (US) 2024-02-28 EP disclosed
EP-4296364-A2 MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS Genomatica, Inc. (US) 2023-12-27 EP disclosed
EP-3967747-B1 MICROORGANISMS AND METHODS FOR IMPROVING PRODUCT YIELDS ON METHANOL USING ACETYL-COA SYNTHESIS GENOMATICA INC (US) 2023-11-08 EP disclosed
US-20230348981-A1 METHODS AND COMPOSITIONS FOR INHIBITING AND TREATING NEUROLOGICAL CONDITIONS POPULATION BIO, INC. 2023-11-02 US disclosed
EP-1451355-A1 METHODS AND SYSTEMS FOR IDENTIFYING NATURALLY OCCURRING ANTISENSE TRANSCRIPTS AND METHODS, KITS AND ARRAYS UTILIZING SAME Compugen Ltd. (IL) 2004-09-01 EP disclosed
US-20040142325-A1 Methods and systems for annotating biomolecular sequences COMPUGEN LTD. (IL) 2004-07-22 US disclosed
US-20040101876-A1 Methods and systems for annotating biomolecular sequences COMPUGEN LTD. (IL) 2004-05-27 US disclosed
US-20040086954-A1 Assay for kinases and phosphatases GOUELI SAID (US) 2004-05-06 US disclosed
US-6720162-B2 PHOSPHORYLATION PROMEGA CORPORATION 2004-04-13 US disclosed
US-20030228618-A1 Methods and systems for identifying naturally occurring antisense transcripts and methods, kits and arrays utilizing same COMPUGEN LTD. (IL) 2003-12-11 US disclosed
WO-2003046220-A1 METHODS AND SYSTEMS FOR IDENTIFYING NATURALLY OCCURRING ANTISENSE TRANSCRIPTS AND METHODS, KITS AND ARRAYS UTILIZING SAME COMPUGEN LTD. (IL) 2003-06-05 WO disclosed
EP-1290213-A2 ASSAY FOR KINASES AND PHOSPHATASES PROMEGA CORPORATION (US) 2003-03-12 EP disclosed
US-20020028477-A1 Assay for kinases and phosphatases PROMEGA CORPORATION 2002-03-07 US disclosed
WO-2001092560-A2 ASSAY FOR KINASES AND PHOSPHATASES PROMEGA CORPORATION (US) 2001-12-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12529078-B2 Microorganisms and methods for improving product yields on methanol using acetyl-CoA synthesis ALDOA, FDPS, DERA ALDH1A1 385/4885KDM4E 409/4885RXFP1 4507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.