Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14088565 | 0.97 | THRB (0.41) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL13991607 | 0.95 | HTT (0.41) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL816380 | 0.92 | ALDH1A1 (0.36) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL12534456 | 0.91 | HTT (0.39) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL12913917 | 0.91 | TSHR (0.36) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL816244 | 0.89 | THRB (0.38) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL15855613 | 0.89 | NPC1 (0.40) | HTTTHRBCYP3A4TSHRNPC1 | |
| SCHEMBL20653505 | 0.89 | CYP1A2 (0.38) | HTTTHRBCYP3A4NPC1LMNA | |
| SCHEMBL19821109 | 0.89 | THRB (0.39) | HTTTHRBCYP3A4ALDH1A1TSHR | |
| SCHEMBL13806736 | 0.89 | ADRB2 (0.36) | HTTTHRBCYP3A4NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410677-B2 | Organosilicon compound-containing polymerizable liquid-crystal composition | CHISSO CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7070838-B2 | Liquid crystalline compound, liquid crystal composition and their polymers | CHISSO PETROCHEMICAL CORPORATION (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20050007541-A1 | Liquid crystalline compound, liquid crystal composition and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2005-01-13 | — | — | US | disclosed |