Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | NCK1 | P16333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5252720 | 0.79 | ALOX5 (0.50) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL1611334 | 0.77 | ALOX5 (0.48) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL6631859 | 0.75 | ALOX5 (0.52) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL29392003 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL8182651 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL87447 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL8182648 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL268706 | 0.75 | ALDH1A1 (0.52) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL8879774 | 0.75 | ALOX5 (0.52) | ALOX5PTGS1PTGS2ALDH1A1TDP1 | |
| SCHEMBL4331368 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7064139-B2 | Method for treating retroviral infections | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2006-06-20 | — | — | US | disclosed |