Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182651 | 0.80 | ALOX5 (0.47) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL20972366 | 0.80 | AMY1A (0.44) | TDP1ALDH1A1LMNACYP1A2CYP2A6 | |
| SCHEMBL5252720 | 0.79 | ALOX5 (0.50) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL1611334 | 0.77 | ALOX5 (0.48) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL8182648 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL6631859 | 0.75 | ALOX5 (0.52) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL87447 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL268706 | 0.75 | ALDH1A1 (0.52) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL8879774 | 0.75 | ALOX5 (0.52) | ALOX5PTGS1PTGS2TDP1ALDH1A1 | |
| SCHEMBL5953422 | 0.75 | ALOX5 (0.47) | ALOX5PTGS1PTGS2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707231-B1 | ANTI-FOAM COMPOSITIONS | PROCTER & GAMBLE (US) | 2021-12-01 | — | — | EP | claimed |
| EP-3707231-A1 | ANTI-FOAM COMPOSITIONS | The Procter and Gamble Company (US) | 2020-09-16 | — | — | EP | claimed |
| EP-3707231-B1 | ANTI-FOAM COMPOSITIONS | PROCTER & GAMBLE (US) | 2021-12-01 | — | — | EP | disclosed |
| US-20200392428-A1 | ANTIFOAMING AGENT AND METHOD FOR MANUFACTURING ANTIFOAMING AGENT | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-12-17 | — | — | US | disclosed |
| US-10836981-B2 | Anti-foam compositions comprising an organopolysiloxane with adjacent hydrolysable groups | THE PROCTER & GAMBLE COMPANY (US) | 2020-11-17 | — | — | US | disclosed |
| EP-3708232-A1 | ANTIFOAMING AGENT AND METHOD FOR MANUFACTURING ANTIFOAMING AGENT | Shin-Etsu Chemical Co., Ltd. (JP) | 2020-09-16 | — | — | EP | disclosed |
| EP-3707231-A1 | ANTI-FOAM COMPOSITIONS | The Procter and Gamble Company (US) | 2020-09-16 | — | — | EP | disclosed |
| US-20190144783-A1 | ANTI-FOAM COMPOSITIONS | THE PROCTER & GAMBLE COMPANY | 2019-05-16 | — | — | US | disclosed |
| US-8895565-B2 | Heterocyclic compound and use of the same | NISHIO TETSUYA (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20110319618-A1 | HETEROCYCLIC COMPOUND AND USE OF THE SAME | NISHIO TETSUYA (JP) | 2011-12-29 | — | — | US | disclosed |
| US-7566683-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-07-28 | — | — | US | disclosed |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-01 | — | — | US | disclosed |
| US-7037880-B2 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-05-02 | — | — | US | disclosed |
| US-20030216394-A1 | Etylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-11-20 | — | — | US | disclosed |
| EP-1360901-A1 | 2,3-cyclic substituted derivatives of 3-hydroxyacrolein and 3-hydroxyacrylic acid as pesticides | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2003-11-12 | — | — | EP | disclosed |
| US-RE38188-E1 | Ethylene derivatives and pesticides containing said derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-0913392-B1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-6462049-B1 | LOW TOXICITY AND PERSISTENT INSECTICIDES AND FUNGICIDES; PREVENTING ATTACHMENT OF AQUATIC ORGANISMS; ECOSYSTEM FRIENDLY; NONPOLLUTING | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| US-6063734-A | AGRICULTURAL CHEMICALS, AGENTS FOR PREVENTING ATTACHMENT OF AQUATIC ORGANISMS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0913392-A1 | ETHYLENE DERIVATIVES AND PEST CONTROLLING AGENTS | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1999-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319618-A1 | HETEROCYCLIC COMPOUND AND USE OF THE SAME | CYP2D6, CYP2B6, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALOX5 3191/4885PTGS1 3006/4885PTGS2 3097/4885 |
| US-20030216394-A1 | Etylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | ALOX5 1107/4885PTGS1 625/4885PTGS2 1295/4885 |
| US-20070049495-A1 | Ethylene derivatives and pesticides containing said derivatives | DDT, ECE1, EBPL | ALOX5 1845/4885PTGS1 641/4885PTGS2 1379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.