SCHEMBL5954472

SCHEMBL5954472

CC(O)C(O)c1ccccn1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
CYP1A2 P05177 2/20 0.47
SLC6A3 Q01959 3/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
KDM4E B2RXH2 3/20 0.46
TSHR P16473 2/20 0.46
KCNA5 P22460 6/20 0.45
KCNH2 Q12809 2/20 0.44
CYP2D6 P10635 2/20 0.44
TP53 P04637 1/20 0.44
ALDH1A1 P00352 2/20 0.42
KCNE1 P15382 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
USP2 O75604 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SLC10A1 Q14973 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887869 1.00 CYP3A4 (0.47) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL20604265 1.00 CYP3A4 (0.47) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL31143650 0.87 CYP3A4 (0.48) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL31143607 0.87 CYP3A4 (0.48) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL7759775 0.87 CYP3A4 (0.48) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL23610049 0.87 CYP3A4 (0.48) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL9777431 0.86 SLC6A2 (0.54) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL4969094 0.83 KDM4E (0.50) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL5227874 0.83 KDM4E (0.50) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4
SCHEMBL24925875 0.83 CYP1A2 (0.47) CYP3A4CYP1A2SLC6A3SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3423433-B1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES BIO PHARM SOLUTIONS CO LTD (KR) 2025-12-17 EP disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses BIO-PHARM SOLUTIONS CO., LTD. (KR) 2019-07-16 US disclosed
EP-3423433-A1 SULFAMATE DERIVATIVE COMPOUNDS, PROCESSES FOR PREPARING THEM AND THEIR USES Bio-Pharm Solutions Co., Ltd. (KR) 2019-01-09 EP disclosed
EP-0948511-B1 CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES SIRNA THERAPEUTICS INC (US) 2006-10-18 EP disclosed
US-6248878-B1 INCLUDING BASES 2-FLUOROPYRIDINE-3-YL, PYRIDINE-2-ONE-3-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-3-YL, 2-BROMOPYRIDINE-5-YL , PYRIDIN-2-ONE-5-YL, 2-AMINOPYRIDINE-5-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-5-YL; ANTISENSE/ANTICANCER AGENTS RIBOZYME PHARMACEUTICALS, INC. 2001-06-19 US disclosed
EP-0948511-A2 CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-10-13 EP disclosed
WO-1998028317-A2 SYNTHESIS OF NUCLEOSIDES AND POLYNUCLEOTIDES RIBOZYME PHARMACEUTICALS, INC. (US) 1998-07-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351519-B2 Sulfamate derivative compounds, processes for preparing them and their uses STS, SULT2A1, SULT1A1 CYP3A4 1003/4885CYP1A2 911/4885SLC6A3 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.