Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23610049 | 1.00 | CYP3A4 (0.48) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL31143650 | 1.00 | CYP3A4 (0.48) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL31143607 | 1.00 | CYP3A4 (0.48) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL30887869 | 0.87 | CYP3A4 (0.47) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL20604265 | 0.87 | CYP3A4 (0.47) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL5954472 | 0.87 | CYP3A4 (0.47) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL9777431 | 0.86 | SLC6A2 (0.54) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL5227874 | 0.83 | KDM4E (0.50) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL4969094 | 0.83 | KDM4E (0.50) | CYP3A4SLC6A3SLC6A2SLC6A4KCNH2 | |
| SCHEMBL1193974 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4328219-A1 | SOS1 DEGRADING AGENT AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-02-28 | — | — | EP | disclosed |
| US-11130734-B2 | Amino alcohol-boron-binol complex and method for preparing optically active amino alcohol derivative by using same | MOLECULES & MATERIALS CO., LTD. (KR) | 2021-09-28 | — | — | US | disclosed |
| US-20210206719-A1 | AMINO ALCOHOL-BORON-BINOL COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE BY USING SAME | MOLECULES & MATERIALS CO., LTD. (KR) | 2021-07-08 | — | — | US | disclosed |
| CN-113072486-A | Amino alcohol-boron-binaphthol complex and preparation method of optically active amino alcohol derivative using same | 分子与物质株式会社 | 2021-07-06 | — | — | CN | disclosed |
| US-11014871-B2 | “Multi-target” compounds with inhibitory activity towards histone deacetylases and tubulin polymerisation, for use in the treatment of cancer | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2021-05-25 | — | — | US | disclosed |
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-20190023645-A1 | \"MULTI-TARGET\" COMPOUNDS WITH INHIBITORY ACTIVITY TOWARDS HISTONE DEACETYLASES AND TUBULIN POLYMERISATION, FOR USE IN THE TREATMENT OF CANCER | UNIVERSITE PARIS-SUD (FR) | 2019-01-24 | — | — | US | disclosed |
| EP-2951180-B1 | 2,6,7,8 SUBSTITUTED PURINES AS HDM2 INHIBITORS | MERCK SHARP & DOHME (US) | 2018-05-02 | — | — | EP | disclosed |
| US-9540377-B2 | 2,6,7,8 substituted purines as HDM2 inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9469608-B2 | Thrombin inhibitors | MERCK SHARP & DOHME CORP. (US) | 2016-10-18 | — | — | US | disclosed |
| US-8354403-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-8354403-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME, CORP. (US) | 2012-06-21 | — | — | US | disclosed |
| CN-1085218-C | Olefin polymerization catalyst | ASAHI CHEMICAL IND (JP) | 2002-05-22 | — | — | CN | disclosed |
| US-6214954-B1 | HOMO OR COPOLYMERIZING AN OLEFIN WITH POLYMERIZATION CATALYST COMPRISING A TRANSITION METAL COMPOUND, CYCLOPENTADIENYL RING CONTAINING LIGAND AND A CHELATING LIGAND, PRODUCES POLYMER WITH NARROW MOLECULAR WEIGHT DISTRIBUTION AND UNIFORMITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0798313-B1 | OLEFIN POLYMERIZATION CATALYST | ASAHI CHEMICAL IND (JP) | 2001-03-21 | — | — | EP | disclosed |
| CN-1169736-A | Catalyst for olefin polymerization | ASAHI CHEMICAL IND (JP) | 1998-01-07 | — | — | CN | disclosed |
| EP-0798313-A1 | OLEFIN POLYMERIZATION CATALYST | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |
| EP-0379928-A2 | Aryl- and heteroarylethanol-pyridylalkylamines, process for their preparation and their use as performance stimulators by animals and as anti-adipositas agent | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130734-B2 | Amino alcohol-boron-binol complex and method for preparing optically active amino alcohol derivative by using same | BCAT1, BCAT2, HBS1L | CYP3A4 1769/4885SLC6A3 1166/4885SLC6A2 1343/4885 |
| US-20190023645-A1 | \"MULTI-TARGET\" COMPOUNDS WITH INHIBITORY ACTIVITY TOWARDS HISTONE DEACETYLASES AND TUBULIN POLYMERISATION, FOR USE IN THE TREATMENT OF CANCER | HDAC6, HDAC1, HDAC5 | CYP3A4 2866/4885SLC6A3 4626/4885SLC6A2 4425/4885 |
| US-20120157432-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | ADRB3, ADRB1, ADRB2 | CYP3A4 854/4885SLC6A3 369/4885SLC6A2 553/4885 |
| US-11014871-B2 | “Multi-target” compounds with inhibitory activity towards histone deacetylases and tubulin polymerisation, for use in the treatment of cancer | HDAC6, HDAC1, HDAC5 | CYP3A4 2927/4885SLC6A3 4587/4885SLC6A2 4404/4885 |
| US-20210206719-A1 | AMINO ALCOHOL-BORON-BINOL COMPLEX AND METHOD FOR PREPARING OPTICALLY ACTIVE AMINO ALCOHOL DERIVATIVE BY USING SAME | BCAT1, BCAT2, HBS1L | CYP3A4 1627/4885SLC6A3 1120/4885SLC6A2 1133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.