Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178554 | 0.82 | ACHE (0.60) | ACHECA1CA2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL5774500 | 0.82 | ACHE (0.60) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL12870325 | 0.81 | ACHE (0.58) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL9781293 | 0.81 | ACHE (0.58) | ACHECA1CA2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL3657271 | 0.81 | ACHE (0.58) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL27493711 | 0.79 | HPGD (0.63) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL31500690 | 0.79 | HPGD (0.63) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL31500691 | 0.79 | HPGD (0.63) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL4898808 | 0.78 | CA1 (0.55) | ACHECA1CA2HPGDALDH1A1 | |
| SCHEMBL12597533 | 0.78 | CA1 (0.55) | ACHECA1CA2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692096-A1 | HYDROXYLAMINE DERIVATIVES | Newron Pharmaceuticals S.p.A. (IT) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005058800-A1 | HYDROXYLAMINE DERIVATIVES | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-06-30 | — | — | WO | disclosed |