Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5955161 | 0.98 | ADAM17 (0.86) | ADAM17TNF | |
| SCHEMBL5955623 | 0.93 | ADAM17 (0.72) | ADAM17TNF | |
| SCHEMBL5954909 | 0.90 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL10131244 | 0.89 | ADAM17 (0.76) | ADAM17TNF | |
| SCHEMBL12860699 | 0.85 | ADAM17 (1.00) | ADAM17TNF | |
| SCHEMBL5954878 | 0.85 | ADAM17 (0.76) | ADAM17TNF | |
| SCHEMBL5955491 | 0.84 | ADAM17 (0.81) | ADAM17TNF | |
| SCHEMBL5956057 | 0.84 | ADAM17 (0.81) | ADAM17TNF | |
| SCHEMBL5955196 | 0.83 | ADAM17 (0.95) | ADAM17TNF | |
| SCHEMBL5955119 | 0.83 | ADAM17 (0.95) | ADAM17TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178553-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178553-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100120838-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2010-05-13 | — | — | US | disclosed |
| US-20100120838-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | SCHERING CORPORATION | 2010-05-13 | — | — | US | disclosed |
| US-7683088-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-7683088-B2 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION (US) | 2010-03-23 | — | — | US | disclosed |
| US-20070265299-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-20070265299-A1 | Compounds for the treatment of inflammatory disorders | SCHERING CORPORATION | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120838-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS | ADAMTS1, ADAMTS13, ADAMTS7 | ADAM17 13/4885TNF 5/4885 |
| US-20070265299-A1 | Compounds for the treatment of inflammatory disorders | ADAMTS1, ADAMTS13, ADAMTS7 | ADAM17 13/4885TNF 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.