Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490913 | 0.84 | DPP4 (0.47) | GPR119DPP4DPP8DPP9DPP7 | |
| SCHEMBL4233275 | 0.83 | ALDH1A1 (0.44) | GPR119ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL896038 | 0.83 | DPP4 (0.51) | GPR119DPP4DPP8DPP9DPP7 | |
| SCHEMBL3352709 | 0.79 | MAPT (0.57) | GPR119ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL26255120 | 0.77 | ALDH1A1 (0.47) | GPR119ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL3310715 | 0.74 | MALT1 (0.46) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL14709651 | 0.74 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EMAPTMAPK1HTT | |
| SCHEMBL27775216 | 0.73 | CYP2C19 (0.50) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL16803444 | 0.73 | SMN1; SMN2 (0.61) | KDM4EHRH3LMNAKMT2A | |
| SCHEMBL12813874 | 0.72 | ALDH1A1 (0.55) | GPR119ALDH1A1KDM4EMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128755-A1 | Amide derivative | AJINOMOTO CO. INC (JP) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128755-A1 | Amide derivative | NR0B1, NR0B2, NR1I3 | GPR119 361/4885DPP4 4297/4885DPP8 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.