Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5805020 | 0.84 | ALDH1A1 (0.40) | MAPTCTNNB1L3MBTL1IRAK4ADORA2A | |
| SCHEMBL5802580 | 0.84 | KDM4E (0.37) | MAPTCTNNB1L3MBTL1IRAK4ADORA2A | |
| SCHEMBL5803267 | 0.76 | CA1 (0.38) | MAPTADORA2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5806830 | 0.73 | GRM2 (0.36) | — | |
| SCHEMBL5803281 | 0.71 | LMNA (0.39) | MAPTL3MBTL1CA12CA2HTT | |
| SCHEMBL1062600 | 0.67 | CA1 (0.33) | ALDH1A1HSD17B10CA12CA2 | |
| SCHEMBL7091675 | 0.65 | CTNNB1 (0.55) | MAPTCTNNB1L3MBTL1IRAK4ALDH1A1 | |
| SCHEMBL3792765 | 0.62 | KDM4E (0.46) | MAPTALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL22891138 | 0.62 | ALDH1A1 (0.35) | ADORA2AADORA1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28482368 | 0.62 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142269-A1 | New compounds | BIOVITRUM AB (SE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142269-A1 | New compounds | GPR119, GLP1R, IAPP | MAPT 1446/4885CTNNB1 4556/4885L3MBTL1 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.