Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14082398 | 0.83 | RAB9A (0.69) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL24307603 | 0.82 | AHR (0.45) | AHRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL15344111 | 0.82 | PIK3CA (0.53) | CCR1CCR5CCR8MAPTKDM4E | |
| SCHEMBL25941110 | 0.81 | RAD52 (0.50) | CCR1CCR5CCR8MAPTKDM4E | |
| SCHEMBL27344644 | 0.79 | CCR1 (0.76) | CCR1CCR5CCR8KDM4ERAB9A | |
| SCHEMBL31695263 | 0.79 | CCR1 (0.76) | CCR1CCR5CCR8KDM4ERAB9A | |
| SCHEMBL27515390 | 0.78 | JAK2 (0.56) | AHRMAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL29932837 | 0.77 | JAK2 (0.60) | MAPTLMNALRRK2HDAC1KDM1A | |
| SCHEMBL14906586 | 0.77 | CBFB (0.66) | MAPTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL827848 | 0.77 | PIK3CA (0.58) | CCR1CCR5CCR8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219453-A1 | PYRAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-05 | — | — | US | disclosed |
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | DODIC NERINA | 2005-11-03 | — | — | US | disclosed |
| EP-1539748-A1 | 2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-06-15 | — | — | EP | disclosed |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | disclosed |
| WO-2004013135-A1 | 2-PHENYLPYRIDIN-4-YL DERIVATIVES AS ALK5 INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245520-A1 | 2-Phenylpyridin-4-yl derivatives as alk5 inhibitors | SMAD2, SMAD3, ALK | CCR1 1244/4885CCR5 327/4885CCR8 1108/4885 |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | BET1, VRK1, VRK2 | CCR1 1604/4885CCR5 1024/4885CCR8 1842/4885 |
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | CCR1 1707/4885CCR5 263/4885CCR8 2319/4885 |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | PGGT1B, BET1, CYP51A1 | CCR1 1267/4885CCR5 669/4885CCR8 1833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.