Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 14/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.59 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956378 | 0.92 | TGFBR1 (0.48) | TGFBR1MAPK14MAT2ASCN10AUSP30 | |
| SCHEMBL5956379 | 0.92 | TGFBR1 (0.48) | TGFBR1MAPK14MAT2ASCN10AUSP30 | |
| SCHEMBL5956439 | 0.89 | TGFBR1 (0.64) | TGFBR1MAPK14NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5956501 | 0.82 | TGFBR1 (0.56) | TGFBR1MAPK14KDR | |
| SCHEMBL5956446 | 0.80 | TGFBR1 (0.61) | TGFBR1MAPK14KDR | |
| SCHEMBL5956677 | 0.79 | TGFBR1 (0.52) | TGFBR1MAPK14 | |
| SCHEMBL5956566 | 0.78 | TGFBR1 (0.52) | TGFBR1MAPK14KDR | |
| SCHEMBL5907522 | 0.78 | MAT2A (0.43) | TGFBR1MAPK14MAT2ASCN10AUSP30 | |
| SCHEMBL5919686 | 0.77 | MAT2A (0.46) | TGFBR1MAPK14MAT2ASCN10AUSP30 | |
| SCHEMBL5956486 | 0.77 | TGFBR1 (0.57) | TGFBR1MAPK14NPC1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004051-A1 | Compounds | DODIC NERINA | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004051-A1 | Compounds | SMAD3, SMAD2, TGFBR1 | TGFBR1 3/4885MAPK14 297/4885MAT2A 1549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.