Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956609 | 1.00 | ROCK2 (0.50) | ROCK2POLBKDM1ARCOR1MAOA | |
| SCHEMBL5956664 | 1.00 | ROCK2 (0.50) | ROCK2POLBKDM1ARCOR1MAOA | |
| SCHEMBL5956622 | 0.95 | ROCK2 (0.49) | ROCK2POLBKDM1ARCOR1MAOA | |
| SCHEMBL5956624 | 0.88 | POLB (0.47) | ROCK2POLBKDM1ARCOR1MAOA | |
| SCHEMBL5956682 | 0.85 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL5956651 | 0.85 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL5956707 | 0.85 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL5956644 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5956600 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5956683 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNAKMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | claimed |
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | claimed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | claimed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | claimed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | claimed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | claimed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | claimed |
| EP-1270570-B1 | AMIDE COMPOUNDS AND USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-05-31 | — | — | EP | disclosed |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2006-01-05 | — | — | US | disclosed |
| US-6933305-B2 | Amide compounds and use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2005-01-20 | — | — | US | disclosed |
| US-20040097436-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-05-20 | — | — | US | disclosed |
| US-6689767-B2 | TRITERPENE BACTERICIDES | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2004-02-10 | — | — | US | disclosed |
| EP-1322661-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-1270570-A1 | AMIDE COMPOUNDS AND USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-09-12 | — | — | US | disclosed |
| US-20020119935-A1 | Triterpenes having antibacterial activity | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2002-08-29 | — | — | US | disclosed |
| WO-2002026762-A1 | TRITERPENES HAVING ANTIBACTERIAL ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002026761-A1 | TRITERPENES HAVING FUNGICIDAL ACTIVITY AGAINST YEAST | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2002-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128210-A1 | Triterpenes having human antifungal and antiyeast activity | ERG28, LSS, MANBA | ROCK2 2869/4885POLB 1315/4885KDM1A 4714/4885 |
| US-20050014730-A1 | Anti-fungal formulation of triterpene and essential oil | BET1, VRK1, VRK2 | ROCK2 1254/4885POLB 1670/4885KDM1A 2445/4885 |
| US-20040097436-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | ROCK2 3529/4885POLB 663/4885KDM1A 4791/4885 |
| US-20060003948-A1 | Compositions that include a triterpene and a carrier | PGGT1B, BET1, CYP51A1 | ROCK2 3638/4885POLB 2698/4885KDM1A 3410/4885 |
| US-20020119935-A1 | Triterpenes having antibacterial activity | BET1, PGGT1B, LSS | ROCK2 3529/4885POLB 663/4885KDM1A 4791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.