Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.57 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956969 | 0.89 | F10 (0.65) | F10CFDKLKB1 | |
| SCHEMBL5956927 | 0.84 | F10 (0.81) | F10 | |
| SCHEMBL5956979 | 0.82 | F10 (0.54) | F10 | |
| SCHEMBL5956996 | 0.80 | F10 (0.54) | F10 | |
| SCHEMBL5956914 | 0.78 | F10 (0.52) | F10CFDKLKB1CYP2C9CYP2C19 | |
| SCHEMBL76485 | 0.77 | F10 (0.81) | F10 | |
| SCHEMBL5956980 | 0.77 | F10 (0.51) | F10CFDKLKB1ALDH1A1CYP2C9 | |
| SCHEMBL5956942 | 0.76 | F10 (0.49) | F10KLKB1 | |
| SCHEMBL5956856 | 0.74 | F10 (0.67) | F10KLKB1 | |
| SCHEMBL5956949 | 0.74 | F10 (0.67) | F10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |