Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956976 | 0.97 | F10 (0.45) | F10MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL5956923 | 0.87 | F10 (0.57) | F10MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5956956 | 0.87 | F10 (0.61) | F10MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL5956933 | 0.84 | F10 (0.58) | F10MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL5956892 | 0.78 | SMN1; SMN2 (0.45) | F10KMT2APOLBLMNAKLKB1 | |
| SCHEMBL79079 | 0.77 | F10 (0.52) | F10MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL5956913 | 0.77 | F10 (0.54) | F10MEN1KMT2ATSHR | |
| SCHEMBL76950 | 0.76 | F10 (0.77) | F10POLB | |
| SCHEMBL5956864 | 0.76 | MEN1 (0.52) | F10MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL5956960 | 0.76 | F10 (0.65) | F10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633346-B1 | PYRROLIDIN-1, 2- DICARBOXYLIC ACID- 1- (4- ETHINYL- PHENYL) - AMID|- 2- (PHENYL)- AMID| DERIVATIVE AS INHIBITORS OF COAGULATION FACTOR XA AND VIIA FOR THE TREATMENT OF THROMBOSIS | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | claimed |