Glutamine

Glutamine

SCHEMBL5957032

CSCC[C@H](N)C(=O)O.C[C@@H](O)[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.N[C@@H](CO)C(=O)O.N[C@@H](CS)C(=O)O

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
PMP22 Q01453 1/20 0.40
KMT2A Q03164 1/20 0.40
FNTA P49354 3/20 0.34
FNTB P49356 3/20 0.34
PGGT1B P53609 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC7A11 Q9UPY5 1/20 0.34
BHMT Q93088 3/20 0.34
BHMT2 Q9H2M3 1/20 0.33
PDCD1LG2 Q9BQ51 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
NOS2 P35228 2/20 0.31
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
RNPEP Q9H4A4 1/20 0.31
GRM8 O00222 1/20 0.30
GRM6 O15303 1/20 0.30
GRIN2D O15399 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL7343863 0.96 PTGS1 (0.37) ALOX15BLMPMP22KMT2AFNTA
Methionine SCHEMBL7343879 0.96 PTGS1 (0.37) ALOX15BLMPMP22KMT2AFNTA
Methionine SCHEMBL7649647 0.89 PTGS1 (0.43) FNTAFNTBPGGT1BPTGS1SLC7A11
Racemethionine SCHEMBL7649637 0.89 PTGS1 (0.43) FNTAFNTBPGGT1BPTGS1SLC7A11
Glutamine SCHEMBL14966644 0.88 ALOX15 (0.43) ALOX15BLMPMP22KMT2APTGS1
Glutamine SCHEMBL1403799 0.86 ALOX15 (0.54) ALOX15BLMPMP22KMT2ABHMT
Glutamine SCHEMBL1403796 0.86 ALOX15 (0.54) ALOX15BLMPMP22KMT2ABHMT
Racemethionine SCHEMBL27554830 0.85 BHMT (0.44) ALOX15BLMPMP22KMT2ABHMT
Arginine SCHEMBL27984034 0.85 FNTA (0.40) ALOX15BLMPMP22KMT2AFNTA
Dl-Phenylalanine SCHEMBL28430093 0.84 ALPI (0.41) ALOX15BLMPMP22KMT2AFNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3904528-A1 DP04 POLYMERASE VARIANTS Stratos Genomics Inc. (US) 2021-11-03 EP disclosed
EP-3056575-A1 POLYMERASES FOR NUCLEOTIDE ANALOGUE INCORPORATION Pacific Biosciences Of California, Inc. (US) 2016-08-17 EP disclosed
CN-101365807-A Polymerases for incorporation of nucleotide analogs PACIFIC BIOSCIENCES CALIFORNIA (US) 2009-02-11 CN disclosed
EP-1666604-A1 Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof The Scripps Research Institute (US) 2006-06-07 EP disclosed