Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8105002 | 0.89 | PTPN1 (0.50) | PTPN1FFAR4SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL1539870 | 0.86 | MAPT (0.59) | PTPN1FFAR4POLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL7262690 | 0.84 | PTPN1 (0.52) | PTPN1PPARDPPARGFFAR4FFAR1 | |
| SCHEMBL5958152 | 0.80 | PTPN1 (0.52) | PTPN1FFAR4SMN1; SMN2L3MBTL1ELANE | |
| SCHEMBL12379065 | 0.79 | PTGER1 (0.53) | PTPN1FFAR4SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6081447 | 0.79 | FFAR4 (0.54) | PTPN1FFAR4FFAR1L3MBTL1LMNA | |
| SCHEMBL1539863 | 0.79 | PTPN1 (0.54) | PTPN1FFAR4SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL8105424 | 0.78 | MAPK1 (0.46) | PTPN1POLBSMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL9702017 | 0.78 | PPARA (0.55) | PTPN1PPARGFFAR4SMN1; SMN2 | |
| SCHEMBL16075023 | 0.78 | MAPT (0.54) | PTPN1FFAR4SMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060094737-A1 | Novel uracil derivatives and medicinal use thereof | SUMITOMO PHARMACEUTICALS CO. LTD. (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1541562-A1 | NOVEL URACIL DERIVATIVES AND MEDICINAL USE THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2005-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094737-A1 | Novel uracil derivatives and medicinal use thereof | HRH3, HRH4, HRH2 | PTPN1 4688/4885PPARD 4564/4885PPARG 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.