SCHEMBL5959946

SCHEMBL5959946

CCC#CCCCCCCCCCCSCC

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.34
PTPN7 P35236 3/20 0.32
HMGCR P04035 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1071138 0.82 TSHR (0.35) TSHRRAB9A
SCHEMBL31336402 0.80 RAB9A (0.48) RAB9APTPN7HMGCR
SCHEMBL5959941 0.79 TRPA1 (0.39) RAB9APTPN7HMGCR
SCHEMBL9007915 0.77 TSHR (0.50) TSHR
SCHEMBL3621240 0.77 RAB9A (0.43) RAB9APTPN7HMGCR
SCHEMBL7155300 0.77 TSHR (0.50) TSHR
SCHEMBL28305438 0.77 TSHR (0.50) TSHR
SCHEMBL23014914 0.77 TSHR (0.32) TSHR
SCHEMBL23014818 0.77 TSHR (0.32) TSHR
SCHEMBL23014718 0.77 LMNA (0.38) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8178713-B2 Sulfur-containing phospholipid derivatives Pronovo Biopharma Norge AS (NO) 2012-05-15 US disclosed
US-8178713-B2 Sulfur-containing phospholipid derivatives Pronovo Biopharma Norge AS (NO) 2012-05-15 US disclosed