SCHEMBL596014

SCHEMBL596014

CCCCCCCCCCCCCCCCCC[SiH2]O[SiH3]

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 6/20 0.33
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC22A1 O15245 1/20 0.33
SMPD1 P17405 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5695346 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL5335209 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18425709 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9237632 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL18425249 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL176365 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL9847969 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL598639 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL7870036 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA
SCHEMBL1231279 1.00 TSHR (0.42) TSHRTHRBDNM1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120028241-A In-situ Moss coding quick addressing micro-array chip unit and preparation method thereof 苏州大学 2025-05-23 CN claimed
CN-116041833-B Flame-retardant foaming sole material and preparation method thereof 福建省莆田市协龙鞋业有限公司 2024-11-29 CN claimed
CN-117887272-A Heat-conducting composite material and preparation method thereof 湖南飞鸿达新材料有限公司 2024-04-16 CN claimed
CN-114813705-B Gas detection equipment based on Raman spectrum 南通朗地罗拉安全设备有限公司 2024-03-19 CN claimed
CN-114858779-B Intelligent gas detection method and device 南通朗地罗拉安全设备有限公司 2024-03-12 CN claimed
CN-116479648-A Janus photo-thermal layer, preparation method thereof and evaporator 深圳大学 2023-07-25 CN claimed
CN-116041833-A Flame-retardant foaming sole material and preparation method thereof 福建省莆田市协龙鞋业有限公司 2023-05-02 CN claimed
CN-115386255-A Two-dimensional material modified raw lacquer marine anticorrosive paint and preparation method thereof 闽江学院 2022-11-25 CN claimed
CN-114858779-A Intelligent gas detection method and device 南通朗地罗拉安全设备有限公司 2022-08-05 CN claimed
CN-114813705-A Gas detection equipment based on Raman spectrum 南通朗地罗拉安全设备有限公司 2022-07-29 CN claimed
US-6607631-B1 Polymerizable monomer adhesive composition includes a 1,1-disubstituted ethylene monomer and at least one slip additive, where the slip additive causes a polymer film formed from the monomer to have a lower coefficient of friction than in an CLOSURE MEDICAL CORPORATION 2003-08-19 US claimed
US-6488944-B2 APPLYING A MIXTURE COMPRISING POLYMERIZABLE 1,1-DISUBSTITUTED ETHYLENE ADHESIVE MONOMER AND POLYDIMETHYLSILOXANE, A SILOXANE MONOMER OR POLYMER, A FLUORINATED SILOXANE, AND A SILOXANE ON AN AREA OF TISSUE WHERE SCAR TISSUE IS PRESENT CLOSURE MEDICAL CORPORATION 2002-12-03 US claimed
EP-1240265-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE Closure Medical Corporation (US) 2002-09-18 EP claimed
WO-2002020684-A2 ADHESIVE COMPOSITIONS WITH REDUCED COEFFICIENT OF FRICTION CLOSURE MEDICAL CORPORATION (US) 2002-03-14 WO claimed
US-20020012678-A1 1, 1-disubstituted ethylene adhesive compositions containing polydimethysiloxane CLOSURE MEDICAL CORPORATION 2002-01-31 US claimed
WO-2001046327-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE CLOSURE MEDICAL CORPORATION (US) 2001-06-28 WO claimed
US-5837312-A PROTEIN HYDROLYZATES IN BED OF SILICONES ABBOTT LABORATORIES (US) 1998-11-17 US claimed
EP-0309489-A4 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL. VARIAN ASSOCIATES (US) 1989-09-11 EP claimed
EP-0309489-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1989-04-05 EP claimed
WO-1988007886-A1 FUSED-SILICA MICROBORE PACKED CHROMATOGRAPHY COLUMN WITH CHEMICALLY MODIFIED COLUMN WALL VARIAN ASSOCIATES, INC. (US) 1988-10-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020012678-A1 1, 1-disubstituted ethylene adhesive compositions containing polydimethysiloxane COL1A1, CDH1, COL2A1 TSHR 4743/4885THRB 3775/4885DNM1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.