Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.45 |
| ▸ | NQO2 | P16083 | 12/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 12/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1644551 | 0.99 | MTNR1A (0.45) | MTNR1ANQO2MTNR1BACHE | |
| SCHEMBL5960309 | 0.87 | MTNR1A (0.46) | MTNR1ANQO2MTNR1BACHE | |
| Hydrochloric Acid SCHEMBL1646444 | 0.86 | MTNR1A (0.45) | MTNR1ANQO2MTNR1BACHE | |
| SCHEMBL2947131 | 0.84 | MTNR1A (0.41) | MTNR1ANQO2MTNR1BACHE | |
| Hydrochloric Acid SCHEMBL1644618 | 0.84 | ACHE (0.41) | MTNR1ANQO2MTNR1BACHE | |
| SCHEMBL7037093 | 0.81 | MTNR1A (0.50) | MTNR1ANQO2MTNR1B | |
| Hydrochloric Acid SCHEMBL6377152 | 0.80 | MTNR1A (0.49) | MTNR1ANQO2MTNR1B | |
| SCHEMBL7110314 | 0.76 | SIGMAR1 (0.52) | MTNR1ANQO2MTNR1B | |
| Fadolmidine SCHEMBL2641380 | 0.75 | ESR1 (0.59) | MTNR1ANQO2MTNR1B | |
| Fadolmidine SCHEMBL29365481 | 0.75 | ESR1 (0.59) | MTNR1ANQO2MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572198-B1 | NEW PHARMACEUTICAL COMPOUNDS WITH ALPHA2RECEPTOR ACTIVITY | ORION CORP (FI) | 2006-04-19 | — | — | EP | claimed |