SCHEMBL5961501

SCHEMBL5961501

[Pt].c1ccc(CCCc2ccccn2)nc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.67
HRH3 Q9Y5N1 3/20 0.59
HRH4 Q9H3N8 2/20 0.59
CYP1A2 P05177 4/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
CYP2C19 P33261 2/20 0.56
ALDH1A1 P00352 2/20 0.55
LMNA P02545 1/20 0.55
TAAR1 Q96RJ0 1/20 0.55
ALOX15 P16050 1/20 0.55
NAAA Q02083 1/20 0.55
CYP2D6 P10635 1/20 0.52
MAPT P10636 1/20 0.50
LIN28A Q9H9Z2 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HSD17B10 Q99714 1/20 0.48
CHRM2 P08172 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231470 0.97 HRH1 (0.69) HRH1HRH3HRH4CYP1A2SMN1; SMN2
SCHEMBL29485637 0.97 HRH1 (0.69) HRH1HRH3HRH4CYP1A2SMN1; SMN2
Hydrochloric Acid SCHEMBL841530 0.95 HRH1 (0.67) HRH1HRH3HRH4CYP1A2SMN1; SMN2
Hydrochloric Acid SCHEMBL29638137 0.95 HRH1 (0.67) HRH1HRH3HRH4CYP1A2SMN1; SMN2
Bromide SCHEMBL11413053 0.93 HRH1 (0.64) HRH1HRH3HRH4CYP1A2SMN1; SMN2
SCHEMBL726512 0.92 HRH1 (0.76) HRH1HRH3HRH4CYP1A2SMN1; SMN2
Hydrochloric Acid SCHEMBL5827595 0.90 HRH1 (0.73) HRH1HRH3HRH4CYP1A2SMN1; SMN2
SCHEMBL31040594 0.90 HRH1 (0.80) HRH1HRH3HRH4CYP1A2SMN1; SMN2
SCHEMBL4418086 0.90 HRH1 (0.80) HRH1HRH3HRH4CYP1A2SMN1; SMN2
SCHEMBL2843489 0.90 HRH1 (0.80) HRH1HRH3HRH4CYP1A2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3837304-A1 CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2021-06-23 EP disclosed
WO-2020035151-A1 CROSSLINKABLE ORGANOYSILOXANE COMPOSITIONS WACKER CHEMIE AG (DE) 2020-02-20 WO disclosed
EP-3487599-A1 DEFOAMING FORMULATIONS CONTAINING ORGANOPOLYSILOXANES Wacker Chemie AG (DE) 2019-05-29 EP disclosed
EP-3374365-A1 METHOD FOR PRODUCING 4-(DIALKYLCHLOROSILYL)-BUTYRONITRILE Wacker Chemie AG (DE) 2018-09-19 EP disclosed
US-7153912-B2 use of branched, alkenyl-functional organopolysiloxanes made by reacting an 1,2,4-trivinylcyclohexane with an organopolysiloxane having Si-bonded hydrogen atoms, using a hydrosilylation catalyst; use in high speed coating of substrates such as paper WACKER CHEMIE AG (DE) 2006-12-26 US disclosed
EP-0545591-B1 Heat curable organopolysiloxane compositions and preformed latent platinum catalysts GEN ELECTRIC (US) 1997-02-05 EP disclosed
US-5432140-A Complex of platinum and organic nitrogen compound GENERAL ELECTRIC COMPANY (US) 1995-07-11 US disclosed
US-5331075-A Blend of polysiloxanes, one containing vinyl group and the other a silicon hydride group GENERAL ELECTRIC COMPANY (US) 1994-07-19 US disclosed
EP-0545591-A1 Heat curable organopolysiloxane compositions and preformed latent platinum catalysts GENERAL ELECTRIC COMPANY (US) 1993-06-09 EP disclosed