Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 2/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11413053 | 0.98 | HRH1 (0.64) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL231470 | 0.97 | HRH1 (0.69) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL29485637 | 0.97 | HRH1 (0.69) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5827595 | 0.95 | HRH1 (0.73) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29638137 | 0.95 | HRH1 (0.67) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL5961501 | 0.95 | HRH1 (0.67) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL726512 | 0.92 | HRH1 (0.76) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL31040594 | 0.90 | HRH1 (0.80) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL4418086 | 0.90 | HRH1 (0.80) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 | |
| SCHEMBL2843489 | 0.90 | HRH1 (0.80) | HRH1HRH3HRH4CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222951-A | HALOGEN-HETEROCYCLE-PLATINUM COMPLEXES AS CATALYSTS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-09-16 | — | — | US | claimed |
| CN-119552366-A | Fluorine-containing organosilicon antifogging additive, and preparation method and application thereof | 中科院广州化学有限公司 | 2025-03-04 | — | — | CN | disclosed |
| WO-2024132121-A1 | RELEASE COATING COMPOSITION | WACKER CHEMIE AG (DE) | 2024-06-27 | — | — | WO | disclosed |
| US-20240182748-A1 | COMPOSITION AND A PROCESS FOR FORMING AN INSULATED MEMBER USING THE SAME | WACKER CHEMIE AG (DE) | 2024-06-06 | — | — | US | disclosed |
| EP-4342947-A1 | SILICONE RUBBER COMPOSITION HAVING EXCELLENT FIREPROOF PERFORMANCE | KCC Silicone Corporation (KR) | 2024-03-27 | — | — | EP | disclosed |
| EP-4204478-B1 | SILICONE COMPOSITION, METHOD OF MAKING THE SAME, AND CABLE MADE FROM THE SAME | WACKER CHEMIE AG (DE) | 2024-03-20 | — | — | EP | disclosed |
| US-11931673-B2 | Defoaming formulations containing organopolysiloxanes | WACKER CHEMIE AG (DE) | 2024-03-19 | — | — | US | disclosed |
| US-11925883-B2 | Defoaming formulations containing organopolysiloxanes | WACKER CHEMIE AG (DE) | 2024-03-12 | — | — | US | disclosed |
| CN-114929838-B | Liquid crystal emulsifying method and liquid crystal emulsion | 瓦克化学股份公司 | 2024-03-01 | — | — | CN | disclosed |
| EP-4323455-A1 | COMPOSITION AND A PROCESS FOR FORMING AN INSULATED MEMBER USING THE SAME | Wacker Chemie AG (DE) | 2024-02-21 | — | — | EP | disclosed |
| US-4618389-A | ALKENYLTRITHYDROCARBONOXYSILANE | SWS SILICONES CORPORATION (US) | 1986-10-21 | — | — | US | disclosed |
| US-4546164-A | Process for preparing a one-component organopolysiloxane composition | SWS SILICONES CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| EP-0124865-A2 | A process for bonding heat curable silicone rubber to a substrate using an aqueous primer composition | Wacker Silicones Corporation (US) | 1984-11-14 | — | — | EP | disclosed |
| US-4456542-A | Method for imparting hydrophobic properties to fibers | WACKER CHEMIE GMBH (DE) | 1984-06-26 | — | — | US | disclosed |
| EP-0110370-A1 | A process for preparing a one-component organopolysiloxane composition | Stauffer-Wacker Silicones Corporation (US) | 1984-06-13 | — | — | EP | disclosed |
| EP-0110371-A1 | One-component electrically conductive organopolysiloxane compositions | Stauffer-Wacker Silicones Corporation (US) | 1984-06-13 | — | — | EP | disclosed |
| US-4454331-A | Process for preparing tetrafluoroethyloxyalkyl silanes | WACKER CHEMIE GMBH (DE) | 1984-06-12 | — | — | US | disclosed |
| US-4387046-A | Electrically conductive organopolysiloxane elastomers | WACKER-CHEMIE (DE) | 1983-06-07 | — | — | US | disclosed |
| US-4276426-A | CATALYTIC ADDITION OF COMPOUND CONTAINING SILICON-BONDED HYDROGEN TO COMPOUND CONTAINING ALIPHATIC MULTIPLE BOND | WACKER-CHEMIE GMBH (DE) | 1981-06-30 | — | — | US | disclosed |
| US-4222951-A | HALOGEN-HETEROCYCLE-PLATINUM COMPLEXES AS CATALYSTS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1980-09-16 | — | — | US | disclosed |