Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9143974 | 0.76 | KDM4E (0.41) | KEAP1L3MBTL1HTTNFE2L2KMT2A | |
| SCHEMBL2245451 | 0.75 | NCF1 (0.38) | — | |
| SCHEMBL3323118 | 0.72 | KEAP1 (0.35) | KEAP1GLO1L3MBTL1ATM | |
| SCHEMBL6662392 | 0.71 | HSD17B10 (0.42) | L3MBTL1NPC1RAB9AKMT2A | |
| SCHEMBL5143503 | 0.71 | KEAP1 (0.47) | KEAP1NR3C2PGRNR3C1AR | |
| SCHEMBL9637938 | 0.71 | IDO1 (0.32) | — | |
| SCHEMBL4723785 | 0.70 | MEN1 (0.33) | NPC1RAB9AKMT2A | |
| SCHEMBL27466799 | 0.70 | — | — | |
| SCHEMBL8877645 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL3174946 | 0.68 | ALDH1A1 (0.44) | ARL3MBTL1ALOX15HTTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002022-A2 | COMPOSITIONS AND METHODS USEFUL FOR THE TREATMENT OF HYPERGLYCEMIA | IMMUSOL INCORPORATED (US) | 2006-01-05 | — | — | WO | disclosed |