Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenethiol SCHEMBL8716345 | 0.87 | KCNH2 (0.45) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL8716349 | 0.87 | KCNH2 (0.45) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL8812966 | 0.87 | KCNH2 (0.45) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL3297154 | 0.85 | KCNH2 (0.43) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL4339471 | 0.85 | CHRM1 (0.35) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL5512763 | 0.82 | LMNA (0.48) | ALDH1A1LMNACRHBPCRHR2SMN1; SMN2 | |
| Toluene SCHEMBL21715053 | 0.76 | LMNA (0.39) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Dioxane SCHEMBL2947014 | 0.75 | TTR (0.43) | SMN1; SMN2TSHR | |
| Benzenethiol SCHEMBL28133317 | 0.73 | ALDH1A1 (0.41) | ALDH1A1CHRM1SLC6A2SLC6A4ADRA1A | |
| Benzenethiol SCHEMBL27710185 | 0.72 | TP53 (0.45) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113151261-A | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107002082-B | Antisense oligonucleotides as inhibitors of TGF-R signaling | 神经视觉医药有限公司 | 2021-02-02 | — | — | CN | disclosed |
| US-7115738-B2 | Hydroxyproline/phosphono oligonucleotide analogues, methods of synthesis and methods of use | ACTIVE MOTIF (US) | 2006-10-03 | — | — | US | disclosed |
| US-6962906-B2 | Oligonucleotide analogues, methods of synthesis and methods of use | ACTIVE MOTIF (US) | 2005-11-08 | — | — | US | disclosed |
| EP-1263773-A4 | OLIGONUCLEOTIDE ANALOGUES, METHODS OF SYNTHESIS AND METHODS OF USE | ACTIVE MOTIF (US) | 2005-08-31 | — | — | EP | disclosed |
| EP-1481085-A2 | OLIGONUCLEOTIDE ANALOGUES AND METHODS OF USE FOR MODULATING GENE EXPRESSION | Active Motif (US) | 2004-12-01 | — | — | EP | disclosed |
| US-20040014644-A1 | Oligonucleotide analogues and methods of use for modulating gene expression | ACTIVE MOTIF. | 2004-01-22 | — | — | US | disclosed |
| WO-2003068798-A2 | OLIGONUCLEOTIDE ANALOGUES AND METHODS OF USE FOR MODULATING GENE EXPRESSION | ACTIVE MOTIF (US) | 2003-08-21 | — | — | WO | disclosed |
| US-20030059789-A1 | Oligonucleotide analogues, methods of synthesis and methods of use | ACTIVE MOTIF | 2003-03-27 | — | — | US | disclosed |
| EP-1263773-A1 | OLIGONUCLEOTIDE ANALOGUES, METHODS OF SYNTHESIS AND METHODS OF USE | Active Motif (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-1989009221-A1 | OLIGONUCLEOTIDE N-ALKYLPHOSPHORAMIDATES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1989-10-05 | — | — | WO | disclosed |
| US-4853327-A | THE PRECURSOR, AN OXIDIZING AGENT, PEROXIDASE, NITROGENEOUS COMPOUND AND ALKYLAMINE; DETECTION OF NUCLEIC ACID HYBRIDS AND PEROXIDASES; IMMUNOASSAY | MOLECULAR DIAGNOSTICS, INC. (US) | 1989-08-01 | — | — | US | disclosed |
| US-4818681-A | Fast and specific immobilization of nucleic acids to solid supports | MOLECULAR DIAGNOSTICS, INC. (US) | 1989-04-04 | — | — | US | disclosed |
| US-4808520-A | HYBRIDIZING WITH NUCLEIC ACID, THEN WITH NUCLEOSIDE TRIPHOSPHATE IN PRESENCE OF ENZYME | MOLECULAR DIAGNOSTICS, INC. (US) | 1989-02-28 | — | — | US | disclosed |
| US-4794073-A | Detection of nucleic acid hybrids by prolonged chemiluminescence | MOLECULAR DIAGNOSTICS, INC. (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0292128-A1 | Improved DNA probes | TAMIR BIOTECHNOLOGY LTD (IL) | 1988-11-23 | — | — | EP | disclosed |
| EP-0210449-A2 | Prolonged chemiluminescence | MILES INC. (US) | 1987-02-04 | — | — | EP | disclosed |
| EP-0198207-A1 | Specific iodination of nucleic acid | MOLECULAR DIAGNOSTICS, INC. (US) | 1986-10-22 | — | — | EP | disclosed |
| EP-0194545-A2 | Labelling of oligonucleotides | MOLECULAR DIAGNOSTICS, INC. (US) | 1986-09-17 | — | — | EP | disclosed |
| EP-0192197-A2 | Fast and specific immobilization of nucleic acids to solid supports | MOLECULAR DIAGNOSTICS, INC. (US) | 1986-08-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014644-A1 | Oligonucleotide analogues and methods of use for modulating gene expression | CRYAA, SRRT, HIRA | ALDH1A1 2513/4885CHRM1 3753/4885SLC6A2 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.