Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.40 |
| ▸ | RELA | Q04206 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952469 | 0.84 | NR1H4 (0.54) | ALOX12NR1H4ALOX5CYP3A4CYP2C9 | |
| SCHEMBL2755032 | 0.84 | ALOX5 (0.40) | ALOX12ALOX15NR1H4ALOX5CYP3A4 | |
| SCHEMBL677785 | 0.83 | ESR2 (0.42) | ALOX12ALOX15NR1H4ALOX5ESR2 | |
| SCHEMBL4408650 | 0.80 | RARA (0.40) | ALOX12ALOX15NR1H4GAAESR2 | |
| SCHEMBL16092805 | 0.79 | BACE1 (0.51) | NR1H4ALOX5CYP3A4SMN1; SMN2MAPT | |
| SCHEMBL616913 | 0.77 | ALOX15 (0.46) | ALOX12ALOX15NR1H4NPC1RAB9A | |
| SCHEMBL2069736 | 0.77 | ALOX5 (0.51) | NR1H4ALOX5CYP3A4NPC1RAB9A | |
| SCHEMBL2070644 | 0.76 | ESR2 (0.39) | ALOX12ALOX15NR1H4ALOX5NPC1 | |
| SCHEMBL14374106 | 0.76 | ALOX5 (0.47) | ALOX12NR1H4ALOX5NPC1RAB9A | |
| SCHEMBL12946430 | 0.74 | ALOX5 (0.43) | ALOX12NR1H4ALOX5CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189897-B1 | ISOFLAVONE METABOLITES | G J CONSULTANTS PTY LTD (AU) | 2006-10-18 | — | — | EP | disclosed |