Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315040 | 0.80 | MEN1 (0.49) | MEN1KMT2AMMP8ALDH1A1MAPT | |
| SCHEMBL287308 | 0.77 | MMP8 (0.56) | MEN1KMT2AMMP8SMN1; SMN2CYP1A2 | |
| SCHEMBL30062331 | 0.77 | MMP8 (0.56) | MEN1KMT2AMMP8SMN1; SMN2CYP1A2 | |
| SCHEMBL10546414 | 0.77 | CASP1 (0.55) | MEN1KMT2AMMP8ALDH1A1MAPT | |
| SCHEMBL7846833 | 0.73 | MEN1 (0.46) | MEN1KMT2AMMP8ALDH1A1MAPT | |
| SCHEMBL27495661 | 0.73 | MEN1 (0.40) | MEN1KMT2AMMP8ALDH1A1MAPT | |
| SCHEMBL9775596 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL2950703 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL13243841 | 0.73 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7854402 | 0.72 | CHRM1 (0.39) | KMT2AALDH1A1SMN1; SMN2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635642-A1 | ANTIMICROBIAL COMPOSITION COMPRISING A POLYMERIC BIGUANIDE AND A COPOLYMER AND USE THEREOF | Arch UK Biocides Limited (GB) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004100665-A1 | ANTIMICROBIAL COMPOSITION COMPRISING A POLYMERIC BIGUANIDE AND A COPOLYMER AND USE THEREOF | ARCH UK BIOCIDES LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |