Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.33 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | F13A1 | P00488 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | TGM1 | P22735 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26464539 | 0.86 | CYP1A2 (0.47) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL26464450 | 0.86 | CYP1A2 (0.47) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL26464715 | 0.86 | CYP1A2 (0.47) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL26464816 | 0.86 | CYP1A2 (0.47) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL26464083 | 0.86 | CYP1A2 (0.47) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL21637229 | 0.82 | HSD11B1 (0.38) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL21765940 | 0.82 | HSD11B1 (0.38) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29144827 | 0.82 | NR1H2 (0.39) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29144815 | 0.82 | NR1H2 (0.39) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 | |
| SCHEMBL29947782 | 0.82 | NR1H2 (0.39) | HSD11B1CYP1A2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122521-B2 | COMPRISING TRIPEPTIDE UNIT OF THE FORMULA (flp-Yaa-Gly)N, WHERE Yaa IS ANY AMINO ACID, FLP IS 4(R)-FLUORO-L-PROLINE, AND N IS AT LEAST 3; INCREASED STABILITY; STRONGER TRIPLE HELIX THAN NATIVE COLLAGEN; FOR USE SUCH AS IN ARTIFICIAL SKIN | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050004032-A1 | Collagen mimics | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-06 | — | — | US | disclosed |