Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 13/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5963755 | 0.81 | ELANE (0.42) | RIPK1ELANESMN1; SMN2 | |
| SCHEMBL16237822 | 0.80 | ELANE (0.44) | RIPK1ELANE | |
| SCHEMBL5963534 | 0.80 | ELANE (0.44) | RIPK1ELANE | |
| SCHEMBL14050230 | 0.80 | ELANE (0.44) | RIPK1ELANE | |
| SCHEMBL5963538 | 0.77 | ELANE (0.51) | ELANEKMT2ASMN1; SMN2KIF11MEN1 | |
| SCHEMBL7989628 | 0.77 | ELANE (0.44) | RIPK1ELANEKMT2ASMN1; SMN2KIF11 | |
| SCHEMBL5963531 | 0.77 | ELANE (0.44) | RIPK1ELANEKMT2ASMN1; SMN2KIF11 | |
| SCHEMBL9407814 | 0.77 | KMT2A (0.43) | RIPK1ELANEKMT2AHPGDMEN1 | |
| SCHEMBL8487905 | 0.77 | KMT2A (0.43) | RIPK1ELANEKMT2AHPGDMEN1 | |
| SCHEMBL9344671 | 0.77 | KMT2A (0.43) | RIPK1ELANEKMT2AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0681568-B1 | PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND BETA-LACTAM INTERMEDIATES THEREFOR | UNIV NEW YORK STATE RES FOUND (US) | 2006-07-26 | — | — | EP | disclosed |
| US-6218553-B1 | METALLIZATION BY REACTING A BACCATIN III DERIVATIVE WITH A METAL ALKYLDISILAZIDE | THE STATE UNIVERSITY OF NEW YORK AT STONY BROOK | 2001-04-17 | — | — | US | disclosed |
| US-6187916-B1 | Process for the preparation of taxane derivatives and β-lactam intermediates therefor | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2001-02-13 | — | — | US | disclosed |
| EP-0681568-A1 | PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND $g(b)-LACTAM INTERMEDIATES THEREFOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-11-15 | — | — | EP | disclosed |
| WO-1994018164-A1 | PROCESS FOR PREPARATION OF TAXANE DERIVATIVES AND β-LACTAM INTERMEDIATES THEREFOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1994-08-18 | — | — | WO | disclosed |